Pharmaceutical Inhalation Aerosol Technology, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 0824756649
Total Pages : 628 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Pharmaceutical Inhalation Aerosol Technology, Second Edition by : Anthony J. Hickey

Download or read book Pharmaceutical Inhalation Aerosol Technology, Second Edition written by Anthony J. Hickey and published by CRC Press. This book was released on 2003-09-03 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.

The Mechanics of Inhaled Pharmaceutical Aerosols

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Author :
Publisher : Academic Press
ISBN 13 : 9780122569715
Total Pages : 328 pages
Book Rating : 4.5/5 (697 download)

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Book Synopsis The Mechanics of Inhaled Pharmaceutical Aerosols by : Warren H. Finlay

Download or read book The Mechanics of Inhaled Pharmaceutical Aerosols written by Warren H. Finlay and published by Academic Press. This book was released on 2001-07-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mechanics of Inhaled Pharmaceutical Aerosols, An Introduction provides a unique and comprehensive treatment of the mechanics of inhaled pharmaceutical aerosols. The book covers a wide range of topics and many new perspectives are given by drawing on research from a variety of fields. Novel, in-depth expositions of the most common delivery devices are given, including nebulizers, dry powder inhalers and propellant metered dose inhalers. The behaviour of aerosols in the respiratory tract is explained in detail, with complete coverage of the fundamentals of current deposition models. The book begins by providing a comprehensive introduction to aspects of aerosol mechanics that are relevant to inhaled pharmaceutical aerosols. It then gives an exhaustive pedagogical description of the behaviour of evaporating and condensing droplets (both aqueous and propellant-based), an introductory chapter on lung geometry and inhalation patterns, and coverage of relevant aspects of fluid mechanics in the lung. Finally, the book provides invaluable, detailed coverage on the mechanics of common pharmaceutical aerosol delivery systems and deposition in the respiratory tract. Throughout the book are many detailed numerical examples that apply the salient concepts to typical inhaled pharmaceutical aerosols. This book will be of interest to scientists and engineers involved in the research and development of inhaled pharmaceutical aerosol products. Experienced practitioners will find many new perspectives that will greatly enhance their understanding of this complex and rapidly growing field. For those delivering therapeutic agents to the lung, this book is a must-have. Students and academics will find this book an invaluable tool and for newcomers it is a worthy guide to the diverse fields that must be understood to work in the area of inhaled pharmaceutical aerosols.

Aerosols Handbook

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Author :
Publisher : CRC Press
ISBN 13 : 0203493184
Total Pages : 728 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Aerosols Handbook by : Lev S. Ruzer

Download or read book Aerosols Handbook written by Lev S. Ruzer and published by CRC Press. This book was released on 2004-12-28 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: As more attention is dedicated to understanding the occupational health risks associated with the industrial manufacture and use of nanotechnology, Aerosols Handbook: Measurement, Dosimetry, and Health Effects is a timely presentation of time-tested research in the field of aerosol science. The book covers a multitude of topics in indoor, outdoor,

Natural Ventilation for Infection Control in Health-care Settings

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Author :
Publisher : World Health Organization
ISBN 13 : 9241547855
Total Pages : 132 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Natural Ventilation for Infection Control in Health-care Settings by : Y. Chartier

Download or read book Natural Ventilation for Infection Control in Health-care Settings written by Y. Chartier and published by World Health Organization. This book was released on 2009 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guideline defines ventilation and then natural ventilation. It explores the design requirements for natural ventilation in the context of infection control, describing the basic principles of design, construction, operation and maintenance for an effective natural ventilation system to control infection in health-care settings.

Aerosols and the Lung

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Author :
Publisher : Elsevier
ISBN 13 : 1483191974
Total Pages : 291 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Aerosols and the Lung by : Stewart W. Clarke

Download or read book Aerosols and the Lung written by Stewart W. Clarke and published by Elsevier. This book was released on 2015-08-11 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aerosols and the Lung covers all aspects of aerosols and the lung, including the use of aerosol in clinical medicine. This volume was developed from the editors' longstanding interest in lung defenses coupled with the radioaerosol technique of assessing their efficiency. This book is organized into 11 chapters. The coverage of these chapters include the physical properties of aerosol required to evaluate their inhalation into the lung, production of aerosol that is suitable for inhalation, determination of aerosol deposition in the lungs and the assessment of lung clearance. This book also highlights the importance of radioaerosols in estimating airway calibre, in detecting airway disease and in ventilation imaging. This book will be of interest to medical students and professionals, particularly those dealing with studies of the human lungs and aerosols.

Essentials of Aerosol Therapy in Critically ill Patients

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Author :
Publisher : Springer Nature
ISBN 13 : 3030850269
Total Pages : 245 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Essentials of Aerosol Therapy in Critically ill Patients by : Mohamed E. A. Abdelrahim

Download or read book Essentials of Aerosol Therapy in Critically ill Patients written by Mohamed E. A. Abdelrahim and published by Springer Nature. This book was released on 2021-10-21 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book assesses the most appropriate forms of aerosol therapy for critically ill patients. Aerosol therapy is applied for the treatment of several pulmonary diseases in addition to some promising applications intended for systemic absorption. Nowadays, aerosol delivery to clinically stable patients in the outpatient settings is done easily with a lot of focus on patient counseling and enhancement of lung deposition. A lot of guidelines are available for several diseases and it could offer adequate guidance to the therapists concerning escalation or de-escalation of therapy to enhance treatment efficiency and safety. However, in critically ill patients aerosol delivery is mostly done by the choice of the respiratory therapist only according to his knowledge. The book describes the type of patients requiring aerosol therapy, different aerosol generators available for the treatment of critically ill patients, mechanisms of aerosol lung deposition, and factors affecting aerosol deposition. It also discusses the special needs of neonates and infants, transitioning aerosol from hospital to home, and the methods of aerosol delivery to different patient e.g. nasal delivery patients, ventilated patients, etc. Moreover, it reviews methods of detecting such aerosol delivery to the lung. At the end, it discusses the suggested monitoring plans and weaning protocols to ensure high efficacy and safety of the ventilatory support in such patients. Given its scope, the book can serve as guidelines or specific recommendations to maximize clinical benefits of medicated aerosols in critically ill patients and it represents a valuable resource for intensivists, pulmonologists and healthcare professionals working at ICUs.

Controlled Pulmonary Drug Delivery

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Publisher : Springer Science & Business Media
ISBN 13 : 1441997458
Total Pages : 560 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Controlled Pulmonary Drug Delivery by : Hugh D.C. Smyth

Download or read book Controlled Pulmonary Drug Delivery written by Hugh D.C. Smyth and published by Springer Science & Business Media. This book was released on 2011-06-24 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents

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Author :
Publisher : National Academies Press
ISBN 13 : 0309102111
Total Pages : 87 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents by : National Research Council

Download or read book Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents written by National Research Council and published by National Academies Press. This book was released on 2006-09-07 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.

Inhaled Medicines

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Publisher : Academic Press
ISBN 13 : 0128149744
Total Pages : 438 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Inhaled Medicines by : Stavros Kassinos

Download or read book Inhaled Medicines written by Stavros Kassinos and published by Academic Press. This book was released on 2021-02-05 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. ? Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact ? Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation ? Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field ? Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues

Respiratory Drug Delivery (1989)

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Author :
Publisher : CRC Press
ISBN 13 : 1351358014
Total Pages : 571 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Respiratory Drug Delivery (1989) by : Peter R. Byron

Download or read book Respiratory Drug Delivery (1989) written by Peter R. Byron and published by CRC Press. This book was released on 2018-04-20 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this book is on subjects related to drug delivery to the lung. The text spans topics from aerosol deposition through pharmaceutical chemistry and formulation to the final clinical evaluation of pharmaceutical products. Utilizing a multi-disciplinary approach, the chapters consider toxicology from the point of view of drugs and pharmaceutical excipients used in aerosols.

Aerosols in Medicine

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Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 462 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Aerosols in Medicine by : Folke Morén

Download or read book Aerosols in Medicine written by Folke Morén and published by Elsevier Publishing Company. This book was released on 1993 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition includes chapters on the diagnostic and therapeutic use of aerosols, systemic therapy, and particle size analysis of therapeutic aerosols. It reviews the current state-of-the-art, details important applications and assesses environmental and occupational aerosols.

Aerosols And The Human Lung: An Introduction

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Publisher : World Scientific
ISBN 13 : 9811212198
Total Pages : 222 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Aerosols And The Human Lung: An Introduction by : Chantal J Darquenne

Download or read book Aerosols And The Human Lung: An Introduction written by Chantal J Darquenne and published by World Scientific. This book was released on 2020-03-10 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the field of aerosol science related to particle inhalation and its effect on the lung, predominately in humans. It covers the basics of aerosol behavior, transport, deposition, clearance, and effects of aerosols, both environmental and therapeutic. Aimed at the researcher entering the field of aerosol inhalation it provides a valuable introductory resource in an accessible format.

Drug Delivery to the Lung

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Author :
Publisher : CRC Press
ISBN 13 : 0824741978
Total Pages : 536 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Drug Delivery to the Lung by : Hans Bisgaard

Download or read book Drug Delivery to the Lung written by Hans Bisgaard and published by CRC Press. This book was released on 2001-10-02 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.

Analytical Chemistry of Aerosols

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Author :
Publisher : Routledge
ISBN 13 : 1351466577
Total Pages : 504 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Analytical Chemistry of Aerosols by : Kvetoslav R. Spurny

Download or read book Analytical Chemistry of Aerosols written by Kvetoslav R. Spurny and published by Routledge. This book was released on 2017-11-22 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until the 1980s, researchers studied and measured only the physical properties of aerosols. Since the 80s, however, interest in the physicochemcal properties of aerosols has grown tremendously. Scientists in environmental hygiene, medicine, and toxicology have recognized the importance held by the chemical composition and properties of aerosols and the interactions of inhaled, "bad" aerosols. This book offers the first comprehensive treatment of modern aerosol analytical methods, sampling and separation procedures, and environmental applications, and offers critical reviews of the latest literature. This important field has developed rapidly in the last 15 years, but until now, no book effectively summarized or analyzed the existing research. Analytical Chemistry of Aerosols reviews procedures, techniques, and trends in the measurement and analysis of atmospheric aerosols. With contributions from acknowledged, international experts, the book discusses various methods of bulk analysis, single particle analysis, and the analysis of special aerosol systems, including fibrous and bacterial aerosols.

Pulmonary Drug Delivery

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Publisher :
ISBN 13 : 9783871933226
Total Pages : 412 pages
Book Rating : 4.9/5 (332 download)

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Book Synopsis Pulmonary Drug Delivery by : Karoline Bechtold

Download or read book Pulmonary Drug Delivery written by Karoline Bechtold and published by . This book was released on 2007-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aerosols, an Industrial and Environmental Science

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Author :
Publisher :
ISBN 13 :
Total Pages : 806 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Aerosols, an Industrial and Environmental Science by : George M. Hidy

Download or read book Aerosols, an Industrial and Environmental Science written by George M. Hidy and published by . This book was released on 1984 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Good,No Highlights,No Markup,all pages are intact, Slight Shelfwear,may have the corners slightly dented, may have slight color changes/slightly damaged spine.

Public Health Consequences of E-Cigarettes

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Author :
Publisher : National Academies Press
ISBN 13 : 030946837X
Total Pages : 775 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Public Health Consequences of E-Cigarettes by : National Academies of Sciences, Engineering, and Medicine

Download or read book Public Health Consequences of E-Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.