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Advancements Of Mass Spectrometry In Biomedical Research
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Book Synopsis Advancements of Mass Spectrometry in Biomedical Research by : Alisa G. Woods
Download or read book Advancements of Mass Spectrometry in Biomedical Research written by Alisa G. Woods and published by Springer. This book was released on 2019-07-25 with total page 813 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.
Book Synopsis Medical Applications of Mass Spectrometry by : Karoly Vekey
Download or read book Medical Applications of Mass Spectrometry written by Karoly Vekey and published by Elsevier. This book was released on 2011-08-11 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.
Book Synopsis Mass Spectrometry in Biomedical Research by : Simon J. Gaskell
Download or read book Mass Spectrometry in Biomedical Research written by Simon J. Gaskell and published by . This book was released on 1986-01-01 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advancements of Mass Spectrometry in Biomedical Research by : Alisa G. Woods
Download or read book Advancements of Mass Spectrometry in Biomedical Research written by Alisa G. Woods and published by Springer. This book was released on 2016-09-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.
Book Synopsis Mass Spectrometry in Biology & Medicine by : A.L. Burlingame
Download or read book Mass Spectrometry in Biology & Medicine written by A.L. Burlingame and published by Springer Science & Business Media. This book was released on 1999-09-14 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading practitioners detail revolutionary new spectrometric techniques for the identification and covalent structural characterization of macromolecules, proteins, glycoconjugates, and nucleic acids. Based on the Fourth International Symposium on Mass Spectrometry in the Health and Life Sciences held in San Francisco in 1998, this invaluable book contains tested strategies for solving many significant biomedical research problems. The techniques use mass spectrometry, automated computer processing of spectral information, and gene, protein, and EST databases for genomic and proteomic correlations. Mass Spectrometry in Biology and Medicine offers a unique opportunity to explore and apply these new techniques of mass spectrometry that are revolutionizing the identification and structural characterization of proteins, carbohydrates, and nucleic acids.
Book Synopsis Sample Preparation in Biological Mass Spectrometry by : Alexander R. Ivanov
Download or read book Sample Preparation in Biological Mass Spectrometry written by Alexander R. Ivanov and published by Springer Science & Business Media. This book was released on 2011-06-15 with total page 1081 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
Book Synopsis Mass Spectrometry of Proteins and Peptides by : Mary S. Lipton
Download or read book Mass Spectrometry of Proteins and Peptides written by Mary S. Lipton and published by Humana Press. This book was released on 2014-11-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the last edition of this book was published in 2000, the field of proteomics was in its infancy. At that time, multidimensional liquid chromatographic separations were being introduced as an alternative to traditional gel-based techniques for separating complex protein and peptide mixtures prior to mass spectrometric detection. Today, this approach – referred to as shotgun proteomics – is considered routine for lar- scale global analyses of protein mixtures. Now in its adolescence, proteomics is fundamentally transforming biological and medical research. Much of this transformation can be attributed to technological advancements, particularly in mass spectrometry. Much wider accessibility of hi- resolution and mass measurement accuracy instrumentation in recent years has ini- ated a new revolution in the field by providing more reliable data and shifting the focus from cataloging proteins to precisely quantifying changes in protein abundance over time and in response to stimuli. Advanced mass spectrometers and novel ion d- sociation schemes such as electron transfer/capture dissociation make it possible to venture boldly into the maze of protein posttranslational modifications, which are an integral component of understanding functional proteomics in the spatial and t- poral domains. Another area that has benefited from these advancements is top-down proteomics, an emerging method essential for characterizing various protein variants that has potentially high impact in biomedical research.
Book Synopsis Mass Spectrometry by : Dominic M. Desiderio
Download or read book Mass Spectrometry written by Dominic M. Desiderio and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the growing use of mass spectrometry in the clinical and biomedical fields, this book collects recent research involving electrospray ionization, neuronal systems, and structural modifications of proteins. The significant advances in instrumentation, methodology, experimentation presented herein will serve to expand the current concept of clinical mass spectrometry.
Book Synopsis Mass Spectrometry-Based Approaches for Treating Human Diseases and Diagnostics by : Thiago Verano-Braga
Download or read book Mass Spectrometry-Based Approaches for Treating Human Diseases and Diagnostics written by Thiago Verano-Braga and published by Springer Nature. This book was released on with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Mass Spectrometry, Volume 12 by : P.G. Kistemaker
Download or read book Advances in Mass Spectrometry, Volume 12 written by P.G. Kistemaker and published by Elsevier. This book was released on 2012-12-02 with total page 975 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings, containing the texts of the invited lectures, cover all aspects of mass spectrometry including theory, fundamental studies, applications and instrumentation. Emphasis is placed on recent developments. A complete listing of the posters is included.
Book Synopsis Advances in Mass Spectrometry in Biochemistry and Medicine by : Alberto Frigerio
Download or read book Advances in Mass Spectrometry in Biochemistry and Medicine written by Alberto Frigerio and published by Halsted Press. This book was released on 1976 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sample Preparation in Biological Mass Spectrometry by : Alexander R. Ivanov
Download or read book Sample Preparation in Biological Mass Spectrometry written by Alexander R. Ivanov and published by Springer. This book was released on 2011-06-17 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
Book Synopsis Applications of Mass Spectrometry in Clinical Chemistry and Biomedical Research by : Mike Aguiar
Download or read book Applications of Mass Spectrometry in Clinical Chemistry and Biomedical Research written by Mike Aguiar and published by . This book was released on 2007 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Clinical chemistry is a medical discipline whose aim is to diagnose and assess disease by analysis of biological specimens. Modem laboratories can perform several hundred different tests using many different methods developed over the last century. The classical, more traditional assays are typically labour-intensive, not multiplexed (only measure one analyte or disorder per assay), expensive, require a long turnaround time, and may not provide adequate sensitivity and specificity. Developments in mass spectrometry (MS) and related technologies over the last two decades have provided solutions for many if not all of these shortcomings. While MS based applications have not yet been widely implemented in clinical chemistry laboratories, current developments will encourage the replacement of traditional methods as well as the expansion of clinically diagnostic endpoints. Indeed, modem MS can be used to simultaneously analyze and quantitate multiple biomarkers in a single analysis. Currently, no other technique exists that can provide a comparable multiplexed analysis. In this thesis, current MS and related technologies were developed and applied to several important but distinct clinical chemistry applications. [...]" --
Book Synopsis Mass Spectrometry in Drug Discovery by : David T. Rossi
Download or read book Mass Spectrometry in Drug Discovery written by David T. Rossi and published by CRC Press. This book was released on 2001-11-07 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry in Drug Discovery summarizes the theory, instrumentation, techniques, and application of mass spectrometry and atmospheric pressure ionization to screening, evaluating, and improving the performance and quality of drug candidates. It provides time- and cost-efficient approaches for the generation and analysis of effective pharmaceuticals, covers advances in combinatorial chemistry, molecular biology, bioanalysis automation, and computing, and demonstrates the use of mass spectrometry in the assessment of disease states, drug targets, and potential drug agents.
Book Synopsis Methodological Advances of MALDI Mass Spectrometry-Based Techniques in Organic and Biomedical Analysis by : Cheng Guo
Download or read book Methodological Advances of MALDI Mass Spectrometry-Based Techniques in Organic and Biomedical Analysis written by Cheng Guo and published by Frontiers Media SA. This book was released on 2022-07-13 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mass Spectrometry and Biomarkers Development by : K.D. Rodland
Download or read book Mass Spectrometry and Biomarkers Development written by K.D. Rodland and published by IOS Press. This book was released on 2004 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major goals of twenty-first century medicine is the identification of biomarkers for the earliest possible stages of disease involvement so that prompt clinical intervention can limit damage, reverse pathological change, and ideally effect a complete cure. New developments in the analytical field of mass spectrometry are providing clinicians and translational scientists with even more powerful tools for the discovery of novel biomarkers. A key requirement for the successful application of mass spectrometric approaches to biomarker discovery is a clear reference standard for the 'normal' human proteome, and a better understanding of the sources and extent of 'normal' variability in human plasma proteins. This special issue of Disease Markers includes examples of biomarker discovery efforts directed at breast and prostate cancers, diabetes mellitus, and heart disease.
Book Synopsis Mass Spectrometry for Metabolomics by : Raúl González-Domínguez
Download or read book Mass Spectrometry for Metabolomics written by Raúl González-Domínguez and published by Springer Nature. This book was released on 2022-09-24 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume provides a comprehensive overview of state-of-the-art metabolomics methods based on mass spectrometry (MS), and their application in food, nutrition, and biomedical research. The chapters assembled herein cover hot topics related to sample preparation, chromatographic and electrophoretic separation, MS-based analysis, as well as data processing and analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mass Spectrometry for Metabolomics serves as a timely guide for chemists, biochemists, biologists, nutritionists, clinicians, and other experts working in the growing and exciting field of metabolomics.
