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Advanced Surface Derivatization Of Superparamagnetic Iron Oxide Nanoparticles In A Fixed Bed Magnetic Reactor For Bio Application
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Book Synopsis Advanced Surface Derivatization of Superparamagnetic Iron Oxide Nanoparticles in a Fixed Bed Magnetic Reactor for Bio-application by : Jatuporn Salaklang
Download or read book Advanced Surface Derivatization of Superparamagnetic Iron Oxide Nanoparticles in a Fixed Bed Magnetic Reactor for Bio-application written by Jatuporn Salaklang and published by . This book was released on 2009 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Superparamagnetic Iron Oxide Nanoparticles by : Morteza Mahmoudi
Download or read book Superparamagnetic Iron Oxide Nanoparticles written by Morteza Mahmoudi and published by . This book was released on 2011 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Superparamagnetic Iron Oxide Nanoparticles by : Morteza Mahmoudi
Download or read book Superparamagnetic Iron Oxide Nanoparticles written by Morteza Mahmoudi and published by . This book was released on 2010-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanoparticles and exploration of their properties have attracted the attention of physicists, chemists, biologists and engineers. Interest in nanoparticles arise from the fact that the mechanical, chemical, electrical, optical, magnetic, electro-optical and magneto-optical properties of these particles are different from their bulk properties and depend on the particle size. There are numerous areas where nanoparticulate systems are of scientific and technological interest. This book reviews research on the various components of superparamagnetic iron oxide nanoparticles.
Book Synopsis Iron Oxide Nanoparticles for Biomedical Applications by : Sophie Laurent
Download or read book Iron Oxide Nanoparticles for Biomedical Applications written by Sophie Laurent and published by Elsevier. This book was released on 2017-10-20 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine. Unlocks the potential of iron oxide nanoparticles to transform diagnostic imaging techniques Contains full coverage of new developments and recent research, making this essential reading for researchers and engineers alike Explains the synthesis, processing and characterization of iron oxide nanoparticles with a view to their use in biomedicine
Book Synopsis Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics by : Sudip Mukherjee
Download or read book Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics written by Sudip Mukherjee and published by Morgan & Claypool Publishers. This book was released on 2019-10-29 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, cancer theranostics applications of magnetic iron oxide nanoparticles are overviewed in details. Moreover, their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity have been briefly highlighted. Finally, we have mentioned the current examples of clinical trials of magnetic nanoparticles in cancer theranostics along with their future scopes and challenges.
Book Synopsis Expanding Applications of Iron Oxide Nanoparticles by Surface Functionalization by : Chuansong Duanmu
Download or read book Expanding Applications of Iron Oxide Nanoparticles by Surface Functionalization written by Chuansong Duanmu and published by . This book was released on 2009 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this dissertation, research efforts mainly focused on exploring the applications of superparamagnetic iron oxide nanoparticles (SPIONs) in MR imaging and nanocatalysis via surface functionalization.
Book Synopsis Engineering Superparamagnetic Iron Oxide Nanoparticles for Environmental Applications by : Wenlu Li
Download or read book Engineering Superparamagnetic Iron Oxide Nanoparticles for Environmental Applications written by Wenlu Li and published by . This book was released on 2015 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineered, superparamagnetic iron oxide nanoparticles (IONPs) have drawn considerable research attention for a broad range of applications based on tunable size and shape, surface chemistries, and magnetic properties. For successful aqueous-based, environmental applications, it is necessary to overcome two, fundamental, yet interconnected challenges: 1) Design and synthesize material which provides information about or effectively induces a relevant reactive pathway at/to the targeted regimes/species, while 2.) Simultaneously, controlling particle stability in/at relevant environmental matrixes/interfaces. In this work, highly monodispersed, single domain, superparamagnetic IONPs, were developed via high temperature decomposition of iron carboxylate salts in an organic phase, with material size (8-40 nm) and morphology precisely controlled through the ratio of precursors, heating rates, reaction times, and addition of cosurfactants (additives). For aqueous evaluation and application, materials were rendered water stable through the development of 13 unique surface bilayer strategies, which were focused on a tunable series of ionic surfactants, varying in chain length, functional group, hydrophobicity, and surface charge. For each bilayer strategy, 8 nm, spherical IONP suspensions were fully characterized with regard to transfer efficiency (into the aqueous phase), aggregation kinetics (varying ionic types/strengths), and long-term aqueous stabilities. Further, for IONPs with oleic acid bilayer coatings, before and after surface (oxidative) aging, extensive evaluation of surface/collector deposition and release behaviors and processes over a range of water chemistries and surface types (hydrophilic vs. hydrophobic) are described using quartz crystal microbalance (QCM) based techniques, among others, highlighting critical aspects of interfacial dynamics for these systems. Finally, IONPs are demonstrated as a platform material for uranyl sorption and separation from water. Specifically, (bilayer) surface optimized, 8-30 nm monodisperse IONPs demonstrate ultra-high uranyl sorption capacities (>50% by wt/wt in some cases). Synchrotron-based X-ray absorption spectroscopic (EXAFS and XANES) analyses indicate that particle size and stabilizing surface functional group(s) significantly affect binding mechanism(s) (e.g. redox based reactions).
Book Synopsis Analytical Applications of Functionalized Magnetic Nanoparticles by : Chaudhery Mustansar Hussain
Download or read book Analytical Applications of Functionalized Magnetic Nanoparticles written by Chaudhery Mustansar Hussain and published by Royal Society of Chemistry. This book was released on 2021-07-27 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic nanoparticles (MNPs) uniquely combine superparamagnetic performance with dimensions that are smaller than or similar size to molecular analytes. Recently, functionalized MNPs are predicted to be a driver for technology and business in this century and hold the promise of high performance materials that will significantly influence all aspects of society. Functionalized MNPs are creating new possibilities for development and innovation in different analytical procedures. Despite their participation in modern development, they are in their infancy and largely unexplored for their practical applications in analysis. This book will provide quality research and practical guidance to analytical scientists, researchers, engineers, quality control experts and laboratory specialists. It covers applications of functionalized MNPs in all stages of analytical procedures. Their incorporation has opened new possibilities for sensing, extraction and detection enabling an increase in sensitivity, magnifying precision and improvement in the detection limit of modern analysis. Toxicity, safety, risk, and legal aspects of functionalized MNPs and the future of analytical chemistry with respect to their use is covered. The book provides an integrated approach for advanced analytical methods and techniques for postgraduates and researchers looking for a reference outlining new and advanced techniques surrounding the applications of functionalized nanomaterials in analytical chemistry.
Book Synopsis Iron Oxide Nanoparticles and Their Applications by : Patricia Villegas
Download or read book Iron Oxide Nanoparticles and Their Applications written by Patricia Villegas and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron oxide nanoparticles demonstrate a number of unique properties, including superparamagnetism, biocompatibility, and non-toxicity, which make them an ideal candidate for a variety of applications, as described in this book. Chapter One deals with the recent advances in various synthetic procedures of iron oxide-based nanocomposites, their characterization methods, and their potential applications in energy storage devices, supercapacitors, fuel cells, and more. Chapter Two summarizes current applications of immobilized enzymes based on iron oxide magnetic nanoparticles and discusses future growth prospects. Chapter Three reviews the properties and applications of enzymatic sensors in exploiting tyrosinase, glucose oxidase, and other enzymes for sensing a broad range of biomedical species. Chapter Four discusses magnetic magnetite and maghemite iron oxide nanoparticles from a variety of perspectives. Chapter Five describes how nano iron oxides could be used to remove pollutants from the environment. Chapter Six provides a comprehensive review of the catalytic applications of iron oxide nanoparticles in organic synthesis, high temperature reactions, gas-phase processes, wastewater treatment and supercritical upgradation of heavy petroleum oils. Chapter Seven details the photocatalytic degradation of a class of toxic, aromatic pollutants, namely, phenols and substituted phenols using different types of photocatalysts in the nano size range for effective removal these compounds from water bodies. Lastly, Chapter Eight elucidates various magnetic nanomaterials-based adsorbents used in adsorption techniques for wastewater treatment.
Book Synopsis Surface Modification of Superparamagnetic Iron Oxide Nanoparticles by : Esther Amstad
Download or read book Surface Modification of Superparamagnetic Iron Oxide Nanoparticles written by Esther Amstad and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2012 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical applications of superparamagnetic iron oxide nanoparticles (NPs) for therapeutic and diagnostic purposes require NPs to be stable under physiologic conditions. This can only be achieved if NPs are sterically stabilized with appropriate dispersants that bind irreversibly to the iron oxide surface. Tight control over the dispersant layer not only prevents NP agglomeration but additionally paves the way to tailor NP size, charge, the type and density of functionalities presented at the NP surface. These factors are especially important for the in vivo performance of NPs. One possibility to sterically stabilize NPs is to graft low molecular weight dispersants to these surfaces. Stabilization of NPs with low molecular weight dispersants relies on high affinity anchors that firmly bind spacers and functionalities to the NP surface at high density. This thesis compares the ability of different anchors to firmly bind low molecular weight dispersants to Fe3O4 NP surfaces and investigates the stability of NPs sterically stabilized with different dispersants. Furthermore, the performance of these sterically stabilized iron oxide NPs in selected biomedical applications is addressed.
Book Synopsis Surface Modifications of Iron Oxide Nanoparticles for Biological Applications by : Numpon Insin
Download or read book Surface Modifications of Iron Oxide Nanoparticles for Biological Applications written by Numpon Insin and published by . This book was released on 2011 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron oxides magnetic nanoparticles (MPs) of high crystallinity, high magnetization, and size-monodispersity were synthesized with oleic acid as their native ligands. These hydrophobic and non-functionalized MPs have magnetic properties that are suitable for various biological applications. Surface modifications were studied for transferring these MPs into biological environments as well as transforming them into functional nanoparticles. Certain surface modifications of MPs, such as attaching silane groups and silica coating, lead to formation of more complex structures of superparamagnetic and fluorescent silica microspheres and nanostructures. These microspheres and nanostructures comprising MPs and semiconductor quantum dots (QDs) are useful tools for biological applications such as for magnetically controlling with fluorescent tracking of particles and for bimodal imaging. Surface modifications of MPs with hydrophobically-modified polyacrylic acid (mPAA) amphiphilic polymer and catechol-derivative surfactants resulted in hydrophilic MPs that are stable in physiological environment and small in their hydrodynamic size. These MPs are also designed to possess active functional groups that are necessary for further conjugations with proteins and molecules of interest. These hydrophilic and functional MPs are useful in biological applications such as magnetic resonance imaging and sensing applications.
Book Synopsis Synthesis, Surface Functionalization, and Biological Testing of Iron Oxide Nanoparticles for Development as a Cancer Therapeutic by : Stanley Eugene Gilliland (III)
Download or read book Synthesis, Surface Functionalization, and Biological Testing of Iron Oxide Nanoparticles for Development as a Cancer Therapeutic written by Stanley Eugene Gilliland (III) and published by . This book was released on 2015 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron oxide nanoparticles are highly researched for their use in biomedical applications such as drug delivery, diagnosis, and therapy. The inherent biodegradable and biocompatible nanoparticle properties make them highly advantageous in nanomedicine. The magnetic properties of iron oxide nanoparticles make them promising candidates for magnetic fluid hyperthermia applications. Designing an efficient iron oxide nanoparticle for hyperthermia requires synthetic, surface functionalization, stability, and biological investigations. This research focused on the following three areas: optimizing synthesis conditions for maximum radiofrequency induced magnetic hyperthermia, designing a simple and modifiable surface functionalization method for specific or broad biological stability, and in vitro and in vivo testing of surface functionalized iron oxide nanoparticles in delivering effective hyperthermia or radiotherapy. The benzyl alcohol modified seed growth method of synthesizing iron oxide nanoparticles using iron acetylacetonate as an iron precursor was investigated to identify significant nanoparticle properties that effect radiofrequency induced magnetic hyperthermia. Investigation of this synthesis under atmospheric conditions revealed a combination of thermal decomposition and oxidation-reduction mechanisms that can produce nanoparticles with larger crystallite sizes and decreased size distributions. Nanoparticles were easily surface functionalized with (3-Glycidyloxypropyl)trimethoxysilane (GLYMO) without the need for organic-aqueous phase transfer methods. The epoxy ring on GLYMO facilitated post-modifications via a base catalyzed epoxy ring opening to obtain nanoparticles with different terminal groups. Glycine, serine, [gamma]-aminobutryic acid (ABA), (S)-( - )-4-amino-2-hydroxybutyric acid (SAHBA), ethylenediamine, and tetraethylenepentamine were successful in modifying GLYMO coated-iron oxide nanoparticles to provide colloidal and varying biological stability while also allowing for further conjugation of chemotherapeutics or radiotherapeutics. The colloidal stability of cationic and anionic nanoparticles in several biologically relevant media was studied to address claims of increased cellular uptake for cationic nanoparticles. The surface functionalized iron oxide nanoparticles were investigated to determine effects on cellular uptake and viability. In vitro tests were used to confirm the ability of iron oxide nanoparticles to provide effective hyperthermia treatment. S-2-(4-Aminobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid (DOTA) was coupled to SAHBA and carboxymethylated polyvinyl alcohol surface functionalized iron oxide nanoparticles and radiolabeled with 177Lu. The capability of radiolabeled iron oxide nanoparticles for delivering radiation therapy to a U87MG murine orthotopic xenograft model of glioblastoma was initially investigated.
Book Synopsis In Vivo Stability and Biodistribution of Superparamagnetic Iron Oxide Nanoparticles Radiolabeled with Indium-111 by : Haotian Wang
Download or read book In Vivo Stability and Biodistribution of Superparamagnetic Iron Oxide Nanoparticles Radiolabeled with Indium-111 written by Haotian Wang and published by . This book was released on 2014 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles of various kinds have generated considerable excitement as vehicles for drug delivery, and as imaging agents (Yen, 2013). Magnetic nanoparticles are of particular interest since their distribution in the body can be manipulated using magnetic fields, and they can also act as highly sensitive contrast agents in magnetic resonance imaging (MRI) (Bonnemain, 1998; Wang, Hussain, & Krestin, 2001). For some applications, radionuclide imaging (Positron emission tomography (PET) or Single-photon emission computed tomography (SPECT)) offers advantages when used in conjunction with MRI, since the strengths of the two modalities, higher spatial resolution for MRI, but better quantification for PET or SPECT, are complementary (Bouziotis et al., 2012). On the other hand, the validity of dual modality imaging requires that the association between radioactive label and magnetic label remains intact in the human or animal body during the period of study. Evaluation of the extent to which this requirement is true for PEGylated nanoparticles containing a core of superparamagnetic iron oxide (SPION), and also labeled with a radioactive metal which is commonly used in nuclear medicine, indium-111, is a major component of this proposal. In the present study, we prepared SPIONs using co-precipitation of iron oxide, complexation with oleic acid, and final coating of the particles with DSPE-PEG plus DMPE-DTPA using the lipid rehydration technique. We radiolabeled the particles by introducing iron-59 ferric chloride or carbon-14 oleic acid during their preparation, and by forming a chelate between the anchored DTPA and indium-111. We conducted biodistribution studies in mice with particles labeled with each radionuclide, and also with indium-111 labeled indium citrate, indium-DTPA, and DMPE-DTPA-indium, and with carbon-14 oleic acid. We found that that the radioactivity from radioindium labeled SPIONs was, as hypothesized, preferentially localized in liver, spleen and bone associated with trapping of colloids by reticuloendothelial cells. However, radioactivity from SPIONs labeled with iron-59 was accumulated in liver, spleen and bone to a greater extent than from indium-111 labeled SPIONs, showing that the association of indium with the particles is not completely maintained in vivo. Radioactivity from SPIONs labeled with carbon-14 oleic acid exhibited a quite different distribution pattern to iron-59 or indium-111, and so does not remain with the iron oxide core after injection into mice.
Book Synopsis Biotransport of Iron Oxide Magnetic Nanoparticles for Biomedical Applications by : Venkatasubramaniam S. Kalambur
Download or read book Biotransport of Iron Oxide Magnetic Nanoparticles for Biomedical Applications written by Venkatasubramaniam S. Kalambur and published by . This book was released on 2007 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Surface Modified Superparamagnetic Iron Oxide Nanoparticles for Long Term Stem Cell Tracking by : A. K. Peacock
Download or read book Surface Modified Superparamagnetic Iron Oxide Nanoparticles for Long Term Stem Cell Tracking written by A. K. Peacock and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications by : Do-Kyung Kim
Download or read book Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications written by Do-Kyung Kim and published by . This book was released on 2001 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Surface Functionalizing Superparamagnetic Iron Oxide Nanoparticles Using Nitrocatechol Anchors by : Esther Amstad
Download or read book Surface Functionalizing Superparamagnetic Iron Oxide Nanoparticles Using Nitrocatechol Anchors written by Esther Amstad and published by . This book was released on 2010 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
