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Author : Junyu Lin
Publisher :
ISBN 13 :
Total Pages : 150 pages
Book Rating : 4.:/5 (89 download)
Download or read book A Yeast Model for Ion-channel ER Export written by Junyu Lin and published by . This book was released on 2002 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Frances M. Ashcroft
Publisher : Academic Press
ISBN 13 : 0080535216
Total Pages : 505 pages
Book Rating : 4.0/5 (85 download)
Download or read book Ion Channels and Disease written by Frances M. Ashcroft and published by Academic Press. This book was released on 1999-10-20 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. - Introduces the relevant aspects of molecular biology and biophysics - Describes the principal methods used to study channelopathies - Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function - Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype
Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2002 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Irena Levitan
Publisher : John Wiley & Sons
ISBN 13 : 1118342305
Total Pages : 396 pages
Book Rating : 4.1/5 (183 download)
Download or read book Cholesterol Regulation of Ion Channels and Receptors written by Irena Levitan and published by John Wiley & Sons. This book was released on 2012-06-12 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health Drawing together and analyzing all the latest research findings, this book explores the role of cholesterol in the regulation of ion channels and receptors, including its pathological effects. It is the first book to comprehensively describe the complex mechanisms by which cholesterol regulates two major classes of membrane proteins. Moreover, it sheds new light on how cholesterol affects essential cellular functions such as the contraction of the heart, propagation of nerve impulses, and regulation of blood pressure and kidney function. Written and edited by leading pioneers in the field, Cholesterol Regulation of Ion Channels and Receptors is divided into three parts: Part I, Cholesterol Regulation of Membrane Properties, introduces the heterogeneity of cholesterol distribution in biological membranes and the physical and biological implications of the formation of cholesterol-rich membrane domains. Part II, Cholesterol Regulation of Ion Channels, examines the mechanisms underlying cholesterol sensitivities of ion channels, including the regulation of ion channels by cholesterol as a boundary lipid. Part III, Cholesterol Regulation of Receptors, explores the latest discoveries concerning how cholesterol regulates distinct types of receptors, including G-protein coupled receptors, LDL and scavenger receptors, and innate immune system receptors. Increased levels of cholesterol represent a major health risk. Understanding cholesterol regulation of ion channels and receptors is essential for facilitating the development of new therapeutic strategies to alleviate the impact of pathological cholesterol conditions. With this book as their guide, readers have access to the most current knowledge in the field.
Author :
Publisher :
ISBN 13 :
Total Pages : 860 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kirk L. Hamilton
Publisher : Springer Nature
ISBN 13 : 3030554546
Total Pages : 1247 pages
Book Rating : 4.0/5 (35 download)
Download or read book Studies of Epithelial Transporters and Ion Channels written by Kirk L. Hamilton and published by Springer Nature. This book was released on 2021-03-04 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.
Author :
Publisher : Academic Press
ISBN 13 : 0323853773
Total Pages : 422 pages
Book Rating : 4.3/5 (238 download)
Download or read book Ion Channels: Channel Production and Optical Methods written by and published by Academic Press. This book was released on 2021-06-05 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion Channels Part B, Volume 652 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including NMDAR, Pannexin, and CALHM, Making NaV1.4 and NaV1.7, TRPVs, Purification native nAChRs, GABAR Radu Aricescu, TRPV5/2, NaV1.5, KATP, TRPA1, TREK-1, SARS-CoV-2 3a ion channel, Ion channel conformational dynamics by encoded unnatural amino acid, Fluorescence lifetime measurement of absolute membrane potential, Fluorescent Toxins as Activity Sensors, FRET Analyses of Ion Channel Protein-Protein Interactions, Control of Ion Channel Gating with Photo-Switchable Tweezers, and Counting Subunits in Kv Channel Complexes. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series
Author :
Publisher : Academic Press
ISBN 13 : 0124079385
Total Pages : 307 pages
Book Rating : 4.1/5 (24 download)
Download or read book Store-Operated Calcium Channels written by and published by Academic Press. This book was released on 2013-07-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject
Author : Horst Feldmann
Publisher : John Wiley & Sons
ISBN 13 : 3527659196
Total Pages : 1 pages
Book Rating : 4.5/5 (276 download)
Download or read book Yeast written by Horst Feldmann and published by John Wiley & Sons. This book was released on 2012-09-06 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, a stand-alone, all-inclusive textbook on yeast biology. Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly expanded, while information on other yeast species has been added, with contributions from additional authors. Naturally, the illustrations are in full color throughout, and the book is backed by a complimentary website. The resulting textbook caters to the needs of an increasing number of students in biomedical research, cell and molecular biology, microbiology and biotechnology who end up using yeast as an important tool or model organism.
Author : Barbara E. Ehrlich
Publisher :
ISBN 13 :
Total Pages : 275 pages
Book Rating : 4.:/5 (64 download)
Download or read book Organellar Ion Channels and Transporters written by Barbara E. Ehrlich and published by . This book was released on 1996 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 2710 pages
Book Rating : 4.3/5 (91 download)
Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2710 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 2068 pages
Book Rating : 4.:/5 (319 download)
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2068 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : R. Wayne Davies
Publisher : Oxford University Press
ISBN 13 : 9780198509981
Total Pages : 512 pages
Book Rating : 4.5/5 (99 download)
Download or read book Molecular Biology of the Neuron written by R. Wayne Davies and published by Oxford University Press. This book was released on 2004-04-08 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a valuable compendium of up-to-date reviews of neuronal molecular biology by leading researchers in the field. It covers all aspects of neuron structure and function, with the emphasis on genetic and molecular analysis.
Author : Mitsuo Tagaya
Publisher : Springer
ISBN 13 : 9811045674
Total Pages : 254 pages
Book Rating : 4.8/5 (11 download)
Download or read book Organelle Contact Sites written by Mitsuo Tagaya and published by Springer. This book was released on 2017-08-16 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future.
Author : Anthony R. Yeo
Publisher : John Wiley & Sons
ISBN 13 : 0470994274
Total Pages : 424 pages
Book Rating : 4.4/5 (79 download)
Download or read book Plant Solute Transport written by Anthony R. Yeo and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad overview of solute transport in plants. It first determines what solutes are present in plants and what roles they play. The physical bases of ion and water movement are considered. The volume then discusses the ways in which solutes are moved across individual membranes, within and between cells, and around the plant. Having dealt with the role of plant solutes in ‘normal’ conditions, the volume proceeds to examine how the use of solutes has been adapted to more extreme environments such as hot, dry deserts, freezing mountains and saline marshes. A crucial stage in the life cycle of most plants, the internally-controlled dehydration concomitant with seed formation, is also addressed. Throughout the volume the authors link our increasing understanding of the cellular and molecular bases of solute movement with the roles that these fulfil in the whole plant under both ideal and stressful conditions, showing how these are dictated by the physical laws that govern solute and water movement. The book is directed at postgraduates, researchers and professionals in plant physiology, biochemistry and molecular biology.
Author : Frances Ashcroft
Publisher : W. W. Norton & Company
ISBN 13 : 0393089541
Total Pages : 367 pages
Book Rating : 4.3/5 (93 download)
Download or read book The Spark of Life: Electricity in the Human Body written by Frances Ashcroft and published by W. W. Norton & Company. This book was released on 2012-09-24 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a wonderful book. Frances Ashcroft has a rare gift for making difficult subjects accessible and fascinating." —Bill Bryson, author of The Body: A Guide for Occupants What happens during a heart attack? Can someone really die of fright? What is death, anyway? How does electroshock treatment affect the brain? What is consciousness? The answers to these questions lie in the electrical signals constantly traveling through our bodies, driving our thoughts, our movements, and even the beating of our hearts. The history of how scientists discovered the role of electricity in the human body is a colorful one, filled with extraordinary personalities, fierce debates, and brilliant experiments. Moreover, present-day research on electricity and ion channels has created one of the most exciting fields in science, shedding light on conditions ranging from diabetes and allergies to cystic fibrosis, migraines, and male infertility. With inimitable wit and a clear, fresh voice, award-winning researcher Frances Ashcroft weaves together compelling real-life stories with the latest scientific findings, giving us a spectacular account of the body electric.
