A Novel Route of Synthesis for Schiff bases derived from 4-Chloro Benzaldehyde with 2 Amino 4-(P-Ethoxy Phenyl) Oxazole

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Author :
Publisher : Microcosmos International Journal of Research
ISBN 13 :
Total Pages : 3 pages
Book Rating : 4./5 ( download)

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Book Synopsis A Novel Route of Synthesis for Schiff bases derived from 4-Chloro Benzaldehyde with 2 Amino 4-(P-Ethoxy Phenyl) Oxazole by : Rajesh Kumar

Download or read book A Novel Route of Synthesis for Schiff bases derived from 4-Chloro Benzaldehyde with 2 Amino 4-(P-Ethoxy Phenyl) Oxazole written by Rajesh Kumar and published by Microcosmos International Journal of Research. This book was released on 2015-11-01 with total page 3 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition metals of 3d series are of immense importance due to their role in biological activity. A number of 3d metals are generally toxic in nature. For example cu having concentration more than 10-9 gm is toxic, it has been observed the toxicity of metal complexes can be reduced by the formation of their transition metal complexes. Keeping above fact in mind a novel route detected for the synthesis of Schiff bases of 3d metal series with 4-chloro benzaldehyde with 2-amino (4-ethoxy phenyl oxazole. The characterization of ligand as well as their metal complexes has been made on the basis of elemental analysis, magnetic susceptibility measurement, Infrared spectra and magnetic moment data.

Side Reactions in Organic Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527604987
Total Pages : 389 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Side Reactions in Organic Synthesis by : Florencio Zaragoza Dörwald

Download or read book Side Reactions in Organic Synthesis written by Florencio Zaragoza Dörwald and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates

Essentials of Organic Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118681967
Total Pages : 711 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Essentials of Organic Chemistry by : Paul M. Dewick

Download or read book Essentials of Organic Chemistry written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2013-03-20 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.

Fluorine-containing Amino Acids

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fluorine-containing Amino Acids by : Valery P. Kukhar

Download or read book Fluorine-containing Amino Acids written by Valery P. Kukhar and published by John Wiley & Sons. This book was released on 1995-04-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, organo-fluorine chemistry has made a marked impact on the design and synthesis of a large variety of biologically active molecules, such as steroids, carbohydrates, amines, amino acids, peptides and other natural products. Naturally occurring amino acids play a pivotal role in living systems, and therefore synthetic fluorine-containing amino acids have been of significant interest to researchers working towards the understanding and modification of physiological processes. Fluorine-containing Amino Acids: is the first volume devoted to the synthesis and properties of fluorine-containing amino acids pays special attention to the preparation of enantiomerically pure acids (which are essential to the modern pharmaceutical industry) deals with a rapidly expanding field of research has been written by experienced researchers who are responsible for many developments in the field highlights the interdisciplinary nature of this topic Fluorine-containing Amino Acids is the only dedicated reference in this subject and will be essential for researchers in synthetic organic, peptide, natural product, and medicinal chemistry and biochemistry.

Dehydroacetic Acid and Its Derivatives

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Author :
Publisher : Elsevier
ISBN 13 : 0081019270
Total Pages : 152 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Dehydroacetic Acid and Its Derivatives by : Santhosh Penta

Download or read book Dehydroacetic Acid and Its Derivatives written by Santhosh Penta and published by Elsevier. This book was released on 2017-03-31 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dehydroacetic Acid and Its Derivatives: Useful Synthons in Organic Synthesis outlines the use of DHA and its derivatives for the synthesis of pharmacologically active heterocyclic compounds. Beginning with an introduction to the chemistry and reactivity of Dehydroacetic Acid, the book goes on to outline the key ring transformation reactions of DHA. The synthesis of various derivatives is then discussed, before a wide range of metal complexes of DHA are explored in detail. The book then concludes with a review of DHA's biological importance and its impressive range of pharmacological activities, including anti-cancer, anti-bacterial, anti-fungal and analgesic properties. For those researching the synthesis of bioactive heterocyclic compounds, this book is a valuable guide on the fundamental knowledge needed to facilitate and enhance the successful synthesis of lead molecules. - Gives detailed information on the underlying chemistry of Dehydroacetic acid and its derivatives - Highlights different approaches for the synthesis of derivatives, including metal complexes - Explores the biological importance of Dehydroacetic Acid

Chemistry for Pharmacy Students

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118687531
Total Pages : 397 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemistry for Pharmacy Students by : Professor Satyajit D. Sarker

Download or read book Chemistry for Pharmacy Students written by Professor Satyajit D. Sarker and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules

Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles

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Author :
Publisher : Elsevier
ISBN 13 : 0128202831
Total Pages : 528 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles by : Navjeet Kaur

Download or read book Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles written by Navjeet Kaur and published by Elsevier. This book was released on 2020-04-25 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. - Highlights new methodologies for the synthesis of different six-membered heterocycles - Provides an up-to-date overview of this fast-moving field with an easy-to-use structure - Includes novel approaches used in the study and application of catalysts in synthetic organic reactions

Animal and Translational Models for CNS Drug Discovery

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Author :
Publisher : Academic Press
ISBN 13 : 0080920411
Total Pages : 1367 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Animal and Translational Models for CNS Drug Discovery by : Robert A. McArthur

Download or read book Animal and Translational Models for CNS Drug Discovery written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-27 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.

Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780470191545
Total Pages : 768 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis by : Henry Feuer

Download or read book Nitrile Oxides, Nitrones and Nitronates in Organic Synthesis written by Henry Feuer and published by John Wiley & Sons. This book was released on 2008-01-02 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive systematization of current novel data in nitrile oxide chemistry, this book authoritatively covers systematic strategies currently used in the preparation and utilization of nitrile oxides, nitrones, and nitronates in organic synthesis. It covers factors governing their stability and includes in-depth information on stable and unstable nitrile oxides. With contributions from leading experts, this is a definitive reference for practicing professionals in organic or medicinal chemistry and an excellent text for students studying organic synthesis.

Hypervalent Iodine Chemistry

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540441077
Total Pages : 275 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Hypervalent Iodine Chemistry by : Thomas Wirth

Download or read book Hypervalent Iodine Chemistry written by Thomas Wirth and published by Springer Science & Business Media. This book was released on 2003-02-12 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: T. Wirth: Introduction and General Aspects.- M. Ochiai: Reactivities, Properties and Structures.- A. Varvoglis: Preparation of Hypervalent Iodine Compounds.- V.V. Zhdankin: C-C-Bond Forming Reactions.- G.F. Koser: C- Heteroatom-Bond Forming Reactions.- G.F. Koser: Heteroatom- Heteroatom-Bond Forming Reactions.- T. Wirth: Oxidations and Rearrangements.- H. Tohma, Y. Kita: Synthetic Applications (Total Synthesis and Natural Product Synthesis).

A Fragrant Introduction to Terpenoid Chemistry

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 178801832X
Total Pages : 432 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis A Fragrant Introduction to Terpenoid Chemistry by : Charles S Sell

Download or read book A Fragrant Introduction to Terpenoid Chemistry written by Charles S Sell and published by Royal Society of Chemistry. This book was released on 2019-05-16 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Terpenoids play an important part in all our lives, from Vitamin A and hormones to perfumes and pharmaceuticals. This book provides an introduction to terpenoid chemistry, concentrating on the lower terpenoids, but the basic principles taught are also the foundation for the chemistry of the higher terpenoids. Coverage includes: the biogenesis of terpenoids; some of the history of the field; the principles of structural determination; and the importance of stereochemistry and stereoselective synthesis. Carbocation chemistry is introduced, as are the principles of total and partial synthesis. Finally, industrial chemistry (both discovery chemistry and chemical process development) is discussed, using the volatile terpenoids of perfumery to illustrate basic concepts. Ideal as both an introduction to terpenoid chemistry and as a refresher course, A Fragrant Introduction to Terpenoid Chemistry, with its real-life problems and appreciation of the relevance of chemistry to everyday life, will prove invaluable to students, lecturers and industrialists alike.

Handbook of Heterocyclic Chemistry

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Publisher : Elsevier
ISBN 13 : 1483293424
Total Pages : 568 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Handbook of Heterocyclic Chemistry by : Alan R. Katritzky

Download or read book Handbook of Heterocyclic Chemistry written by Alan R. Katritzky and published by Elsevier. This book was released on 2017-01-31 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

Nitrile Oxides, Nitrones, and Nitronates in Organic Synthesis

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Author :
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nitrile Oxides, Nitrones, and Nitronates in Organic Synthesis by : Kurt Torssell

Download or read book Nitrile Oxides, Nitrones, and Nitronates in Organic Synthesis written by Kurt Torssell and published by Wiley-VCH. This book was released on 1988 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Organic Synthesis

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Author :
Publisher : Newnes
ISBN 13 : 008097743X
Total Pages : 9815 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Organic Synthesis by :

Download or read book Comprehensive Organic Synthesis written by and published by Newnes. This book was released on 2014-02-14 with total page 9815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Protein Sequence Determination

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Publisher : Springer Science & Business Media
ISBN 13 : 3662128349
Total Pages : 363 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis Protein Sequence Determination by : Saul B. Needleman

Download or read book Protein Sequence Determination written by Saul B. Needleman and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: "All the King's horses and all the King's mm couldn't put Humpty Dumpty together again." It is entirely possible that the difficulty facing "all the King's men" was principally the lack of a sufficient guide to the techniques of reassembling from a series of small components, the original entity. It is the sincere hope of the editor of the present work and of each of the contributing authors that the modern researcher will not face a similar predicament in his endeavours to reconstruct the complete primary sequence of a protein from the array of component amino acids. Rather, it is the intent that, with this volume, he may proceed untimorously if not with outright confidence toward achieving his purpose. To the newcomer in protein sequencing, compelled by necessity, or fascination, to investigate the exact order of amino acids in proteins, the question of "where to begin" - or "how to do it" is urgent. To those more skilled, a ready source of additional techniques should nevertheless be of value. This volume attempts to present in a single source a discussion of the methods and techniques useful to the determination of the primary structures of proteins and peptides. Hopefully, this book will tell the reader "how to do it".

Green Synthetic Approaches for Biologically Relevant Heterocycles

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Author :
Publisher : Elsevier
ISBN 13 : 0128205865
Total Pages : 642 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Green Synthetic Approaches for Biologically Relevant Heterocycles by : Goutam Brahmachari

Download or read book Green Synthetic Approaches for Biologically Relevant Heterocycles written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-02-26 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability

Ruthenium Oxidation Complexes

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Publisher : Springer Science & Business Media
ISBN 13 : 1402093780
Total Pages : 274 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Ruthenium Oxidation Complexes by : William P. Griffith

Download or read book Ruthenium Oxidation Complexes written by William P. Griffith and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ruthenium Oxidation Complexes explores ruthenium complexes, particularly those in higher oxidation states, which function as useful and selective organic oxidation catalysts. Particular emphasis is placed on those systems which are of industrial significance. The preparation, properties and applications of the ruthenium complexes are described, followed by a presentation of their oxidative properties and summary of the different mechanisms involved in the organic oxidations (e.g. oxidations of alcohols, alkenes, arenes and alkynes, alkanes, amines, ethers, phopshines and miscellaneous substrates). Moreover, future trends and developments in the area are discussed. This monograph is aimed at inorganic, organic, industrial and catalysis chemists, especially those who wish to carry out specific organic oxidations using catalytic methods.