Mass Spectrometry

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Publisher : Wiley
ISBN 13 : 9780471485650
Total Pages : 420 pages
Book Rating : 4.4/5 (856 download)

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Book Synopsis Mass Spectrometry by : Edmond de Hoffmann

Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Oxford Textbook of Heart Failure

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Publisher : Oxford University Press
ISBN 13 : 0199577722
Total Pages : 660 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Oxford Textbook of Heart Failure by : Roy S. Gardner

Download or read book Oxford Textbook of Heart Failure written by Roy S. Gardner and published by Oxford University Press. This book was released on 2011-07-14 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally renowned leaders in their field and relevant to all practicing clinicians, this textbook comprehensively covers all aspects of heart failure, and suggests the optimal evidence-based management for heart failure patients.

Handbook of Solid Phase Microextraction

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Publisher : Elsevier
ISBN 13 : 0123914493
Total Pages : 497 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Handbook of Solid Phase Microextraction by : Janusz Pawliszyn

Download or read book Handbook of Solid Phase Microextraction written by Janusz Pawliszyn and published by Elsevier. This book was released on 2011-12-01 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed. This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method. - Practical application of Solid Phase Microextraction methods including detailed steps - Provides history of extraction methods to better understand the process - Suitable for all levels, from beginning student to experienced practitioner

Advances in Forensic Applications of Mass Spectrometry

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Author :
Publisher : CRC Press
ISBN 13 : 0203998286
Total Pages : 300 pages
Book Rating : 4.2/5 (39 download)

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Book Synopsis Advances in Forensic Applications of Mass Spectrometry by : Jehuda Yinon

Download or read book Advances in Forensic Applications of Mass Spectrometry written by Jehuda Yinon and published by CRC Press. This book was released on 2003-12-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in analytical instrumentation have had an enormous influence on forensic analysis. The mass spectrometer is now an integral part of every forensic laboratory, resulting in greater analytical accuracy, more reliable identification, and lower detection limits. As the instrumental method of choice among forensic analysts, the mass

Tandem Mass Spectrometry

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Publisher : BoD – Books on Demand
ISBN 13 : 9535111361
Total Pages : 208 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Tandem Mass Spectrometry by : Ana Varela Coelho

Download or read book Tandem Mass Spectrometry written by Ana Varela Coelho and published by BoD – Books on Demand. This book was released on 2013-05-29 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds. The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series in Tandem Mass Spectrometry serves multiple groups of audiences; professional (academic and industry), graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences.

Clarke's Analytical Forensic Toxicology

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Publisher : Pharmaceutical Press
ISBN 13 : 0857110543
Total Pages : 657 pages
Book Rating : 4.8/5 (571 download)

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Book Synopsis Clarke's Analytical Forensic Toxicology by : Gail Cooper

Download or read book Clarke's Analytical Forensic Toxicology written by Gail Cooper and published by Pharmaceutical Press. This book was released on 2013-05-28 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable textbook, written by international experts, covers all the main elements of forensic toxicology and analytical toxicology techniques as well as the important parts of pharmacokinetics, drug metabolism, and pharmacology in general, with a particular focus on drugs of abuse.

Discovery and Development of Antidiabetic Agents from Natural Products

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Publisher : Elsevier
ISBN 13 : 0128096926
Total Pages : 334 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Discovery and Development of Antidiabetic Agents from Natural Products by : Goutam Brahmachari

Download or read book Discovery and Development of Antidiabetic Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2016-10-11 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications. Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics. - Contains chapters written by active researchers and leading global experts who are deeply engaged in the research field of natural product chemistry for drug discovery - Provides comprehensive coverage of cutting-edge research advances in the design of medicinal natural products with potential as preventives and therapeutics for diabetes and related metabolic issues - Presents a practical review of the identification, isolation, and extraction techniques that help support medicinal chemists in the lab

Isocyanide-based Multicomponent Reactions

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889634841
Total Pages : 100 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Isocyanide-based Multicomponent Reactions by : Jonathan G. Rudick

Download or read book Isocyanide-based Multicomponent Reactions written by Jonathan G. Rudick and published by Frontiers Media SA. This book was released on 2020-02-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology

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Publisher : Frontiers Media SA
ISBN 13 : 2889459721
Total Pages : 107 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology by : Simona Pichini

Download or read book The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology written by Simona Pichini and published by Frontiers Media SA. This book was released on 2019-08-19 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Synthetic Opioids (NSOs), most of which are illegally produced and sold for recreational use, are posing a serious threat to the health of consumers. Due to the low cost of materials and equipment required for clandestine laboratories production with respect to the production cost of heroin, NSOs are climbing the illegal street and web drug market. Several of these drugs have been involved in a recent rise in acute intoxications and overdose deaths. Since NSOs offer enormous profit potential, and there is strong demand for their use, these drugs are being trafficked by organized crime and present major challenges for medical professionals facing intoxications and fatalities, law enforcement agencies fighting against their diffusion and policymakers trying to restrain the use and abuse of NSOs. This Research Topic aimed to fill the gap on current knowledge on pharmacology and toxicology, health risks for adult and newborns of NSOs covering both basic scientific as well as epidemiological and clinical aspects. 3 reviews, 3 mini-reviews, 1 original article, 2 case reports and 1 opinion are here presented.

Basic Principles of Forensic Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 1597454370
Total Pages : 360 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Basic Principles of Forensic Chemistry by : JaVed I. Khan

Download or read book Basic Principles of Forensic Chemistry written by JaVed I. Khan and published by Springer Science & Business Media. This book was released on 2011-11-16 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on a marvel approach that blends chemistry with forensic science and is used for the examination of controlled substances and clandestine operations. The book will particularly interest forensic chemists, forensic scientists, criminologists, and biochemists.

Chemical and Physical Behavior of Human Hair

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Publisher : Springer Science & Business Media
ISBN 13 : 0387216952
Total Pages : 496 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Chemical and Physical Behavior of Human Hair by : Clarence R. Robbins

Download or read book Chemical and Physical Behavior of Human Hair written by Clarence R. Robbins and published by Springer Science & Business Media. This book was released on 2006-05-26 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human hair is the subject of a wide range of scientific investigations. Its chemical and physical properties are of importance to the cosmetics industry, forensic scientists, and to biomedical researchers. This updated and enlarged fourth edition continues the tradition of its predecessor as being the definitive monograph on the subject. It now contains new information on various topics including: chemical hair damage, the cause of dandruff, skin and eye irritation, hair straightening, and others. Chemical and Physical Behavior of Human Hair is a teaching guide and reference volume for cosmetic chemists and other scientists in the hair products industry, academic researchers studying hair and hair growth, textile scientists, and forensic specialists.

Basic Skills in Interpreting Laboratory Data

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Publisher : ASHP
ISBN 13 : 158528274X
Total Pages : 633 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Basic Skills in Interpreting Laboratory Data by : Mary Lee

Download or read book Basic Skills in Interpreting Laboratory Data written by Mary Lee and published by ASHP. This book was released on 2009-02-26 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Basic Skills in Interpreting Laboratory Data, 4th Edition is acase-based learning tool that will enhance your skills in clinical lab test interpretation. It provides fundamentals of interpreting lab test results not only for pharmacy students, but also for practitioners as an aid in assessing patient drug-treatment responses. It is the only text written by and for pharmacists and provides case studies and practical information on patient therapy.Since the publication of the third edition, much has changed—in the clinical lab and in the hospital pharmacy. Consequently, the new fourth edition incorporates significant revisions and a wealth of important new information. NEW TO THIS EDITION: Three new chapters including new information on men’s health, women’s health, and pharmacogenomics and laboratory tests. Mini-cases embedded in each chapter provide therapy-related examples and reinforce important points made in the text. Quickview Charts give an overview of important clinical information including reference ranges and critical values. Learning Points focus on a clinical application of a major concept present in the chapter.

Principles of Nutrigenetics and Nutrigenomics

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Publisher : Academic Press
ISBN 13 : 0128045876
Total Pages : 588 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Nutrigenetics and Nutrigenomics by : Raffaele De Caterina

Download or read book Principles of Nutrigenetics and Nutrigenomics written by Raffaele De Caterina and published by Academic Press. This book was released on 2019-09-22 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. - Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics - Includes a valuable guide to ethics for genetic testing for nutritional advice - Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts - Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Amino Acids in Nutrition and Health

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Author :
Publisher : Springer Nature
ISBN 13 : 3030453286
Total Pages : 218 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Amino Acids in Nutrition and Health by : Guoyao Wu

Download or read book Amino Acids in Nutrition and Health written by Guoyao Wu and published by Springer Nature. This book was released on 2020-08-06 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in all the systems of humans and other animals (including livestock, poultry, companion animals, and fish). It enables readers to understand the crucial roles of amino acids and their metabolites in the health and diseases of the circulatory, digestive, endocrine, immune, muscular, nervous, reproductive, respiratory, skeletal, and urinary systems, as well as the sense organs (eyes, ears, nose, skin, and tongue). Readers will learn that amino acids are not only the building blocks of protein, but are also signalling molecules, as well as regulators of gene expression, metabolic processes and developmental changes in the body. This knowledge will guide nutritional practices to improve the growth, development and health of humans and other animals, as well as prevent and treat chronic (e.g., obesity, diabetes, and cardiovascular disorders) and infectious (e.g., bacterial, fungal, parasite, and viral) diseases. Editor of this volume is an internationally recognized expert in nutritional biochemistry. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals as well as undergraduate and graduate students in animal science, biochemistry, biomedical engineering, biology, human medicine, food science, kinesiology, nursing, nutrition, pharmacology, physiology, toxicology, veterinary medicine, and other related disciplines. In addition, all chapters provide general and specific references to amino acids in systems health for researchers and practitioners in biomedicine, animal and plant agriculture, and aquaculture, and for government policy makers.

Drug-Facilitated Sexual Assault

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Publisher : Elsevier
ISBN 13 : 0080504760
Total Pages : 338 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Drug-Facilitated Sexual Assault by : Marc A. LeBeau

Download or read book Drug-Facilitated Sexual Assault written by Marc A. LeBeau and published by Elsevier. This book was released on 2001-08-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Facilitated Sexual Assault educates readers on the ways in which drugs are used as weapons in committing sexual assaults and how to successfully investigate these crimes. It looks at the history of these crimes over the years, and includes an in-depth discussion of the drugs and drug classes in use today. It describes the effects of these drugs on the victims, the process for reporting these crimes, details on the type of person who uses drugs to sexually assault an individual, and obstacles to investigating the suspect. The authors show the proper techniques in collecting and analyzing evidence; ways to overcome some of the unique difficulties encountered in these types of investigations; and how to work with other professionals to prosecute these cases successfully. The concluding appendixes are valuable samples of the necessary forms needed to complete these investigations. This book is ideal for anyone involved in investigating these crimes, including forensic scientists, law enforcement officers, lawyers, toxicologists, and medical professionals. * Ideal for everyone involved in the investigation of these crimes, including forensic scientists, police officers, lawyers, toxicologists and medical professionals

Medicinal Chemistry

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Publisher : Oxford University Press
ISBN 13 : 0190282967
Total Pages : 664 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Medicinal Chemistry by : Thomas Nogrady

Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

Organic Acids in Man

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Publisher : Springer Science & Business Media
ISBN 13 : 9400957785
Total Pages : 531 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Organic Acids in Man by : R. Chalmers

Download or read book Organic Acids in Man written by R. Chalmers and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: The writing of this book was prompted by the need for a comprehensive of current data on organic acids suitable for both newcomers and collection established researchers in this field. The only previous text of the kind was the excellent review by Nordmann and Nordmann (1961), and at that time the main method of analysis was paper chromatography with liquid chromatography being used in a limited way. Only three diseases in which organic acids accumulate were known (primary hyperoxaluria, phenylketonuria and alcaptonuria). Since then, with the development of gas chromatography and mass spectrometry, and the further development ofliquid chromatography, knowledge concerning the nature of the organic acids in physiological fluids has been greatly extended. At the same time, the number of organic acidurias has increased dramatically, there being now some 40-50 known diseases of this type. During the past 15 years or so, there have been several reviews, dealing with either specific diseases or groups of diseases (Gompertz, 1972, 1974; Tanaka, 1975), or presenting the proceedings of symposia (Stern and Toothill, 1972) or workshops (Marner et al. , 1974). This present text deals comprehensively and in detail with the organic acids in human physiological fluids in health and in disease states, and is particularly concerned with the methods necessary for their separation, determination and indentification.