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A Mechanistic Study
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Book Synopsis Evaluating Evidence of Mechanisms in Medicine by : Veli-Pekka Parkkinen
Download or read book Evaluating Evidence of Mechanisms in Medicine written by Veli-Pekka Parkkinen and published by Springer. This book was released on 2018-07-13 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.
Book Synopsis Pericyclic Reactions by : S. M. Mukherji
Download or read book Pericyclic Reactions written by S. M. Mukherji and published by . This book was released on 1979 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Mechanistic Study of the Oxidation of Some Trialkylamines by : C. A. Audeh
Download or read book A Mechanistic Study of the Oxidation of Some Trialkylamines written by C. A. Audeh and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Theoretical Modelling and Mechanistic Study of the Formation and Atmospheric Transformations of Polycyclic Aromatic Compounds and Carbonaceous Particles by : Antonius Indarto
Download or read book Theoretical Modelling and Mechanistic Study of the Formation and Atmospheric Transformations of Polycyclic Aromatic Compounds and Carbonaceous Particles written by Antonius Indarto and published by Universal-Publishers. This book was released on 2010-06-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Polycyclic Aromatic Hydrocarbons (PAHs) and soot share the same origin (incomplete combustion or pyrolysis) and nature, namely structural and electronic features. The purpose of the research work discussed in this thesis is to offer a theoretical contribution to elucidate some aspects of PAH and soot particle formation. The interest in carrying out such a work lies on one hand in the ubiquitous presence of both species in the environment, on the other hand on the concern for their impact on both human health, specifically involving the respiratory system, and climate, in particular as regards global warming. Thus, a better knowledge on the formation mechanisms of PAHs and soot could then help the efforts to reduce their concentration in our atmosphere. Since the formation mechanisms still presents unclear aspects, the suggestions and indications which can be offered by a theoretical study come out to be complementary to the large amount of experimental data collected so far. In setting up models aimed to mimic what happens in real pyrolysis or combustion situations, we have exploited the fact that PAHs and soot share as a common trait the presence of condensed unsaturated cycles (whose aromatic character can be variable). Thus, though types of soot of different origin will exhibit, on a larger scale, a variety of structural traits, we have chosen an assortment of PAH-like models to study different processes, together with other smaller unsaturated closed and open shell species that are known to play a role in the synthesis course. A preliminary phase of the study was aimed to assess which computational level could be both dependable and affordable to investigate the growth of a PAH-like radical when it is adsorbed onto soot platelets (particle phase). Then the Bittner-Howard variant of the widely accepted Hydrogen Abstraction Acetylene Addition (HACA) growth mechanism has been explored by Density Functional Theory (DFT) at the level mentioned above, both in the gas and particle phases, and over a wide range of temperatures. A parallel mechanism, differing from HACA, based on polyynes and characterized by the proliferation of radical centers, has also been studied for a variety of models at a multiconfigurational theory level. To the end, we have explored several reaction pathways starting from the addition of the propargyl radical to butadiyne.
Book Synopsis Comprehensive Natural Products III by :
Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience
Book Synopsis A Mechanistic Study of the Reactions of Animines with 1-chlorobenzotriazole by :
Download or read book A Mechanistic Study of the Reactions of Animines with 1-chlorobenzotriazole written by and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Mechanistic Study of Complex Base-promoted 1,2-elimination Reactions by : Alan Paul Croft
Download or read book A Mechanistic Study of Complex Base-promoted 1,2-elimination Reactions written by Alan Paul Croft and published by . This book was released on 1983 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Reaction Rates of Isotopic Molecules by : Lars C. S. Melander
Download or read book Reaction Rates of Isotopic Molecules written by Lars C. S. Melander and published by . This book was released on 1987 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Organic Chemistry by : Penny Chaloner
Download or read book Organic Chemistry written by Penny Chaloner and published by CRC Press. This book was released on 2014-12-15 with total page 1272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a different, more engaging approach to teaching and learning, Organic Chemistry: A Mechanistic Approach classifies organic chemistry according to mechanism rather than by functional group. The book elicits an understanding of the material, by means of problem solving, instead of purely requiring memorization. The text enables a deep unders
Book Synopsis A Mechanistic Study of the Olefin Metathesis Reaction by : Terence Kevin Brunck
Download or read book A Mechanistic Study of the Olefin Metathesis Reaction written by Terence Kevin Brunck and published by . This book was released on 1972 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Mechanistic Study of Highly Viscous Fermentations by : Steven See-Shown Lee
Download or read book A Mechanistic Study of Highly Viscous Fermentations written by Steven See-Shown Lee and published by . This book was released on 1989 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Mechanistic Study of Photobromination by : Hans Wilhelm Mueller
Download or read book A Mechanistic Study of Photobromination written by Hans Wilhelm Mueller and published by . This book was released on 1974 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hydrostannation by : André Jan Leusink
Download or read book Hydrostannation written by André Jan Leusink and published by . This book was released on 1966 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Mechanistic Study of Oxygen Transfer in Aqueous Systems by : Charles B. Muchmore
Download or read book A Mechanistic Study of Oxygen Transfer in Aqueous Systems written by Charles B. Muchmore and published by . This book was released on 1970 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mechanism by : Domenico Bertoloni Meli
Download or read book Mechanism written by Domenico Bertoloni Meli and published by University of Pittsburgh Press. This book was released on 2019-04-18 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mechanical philosophy first emerged as a leading player on the intellectual scene in the early modern period—seeking to explain all natural phenomena through the physics of matter and motion—and the term mechanism was coined. Over time, natural phenomena came to be understood through machine analogies and explanations and the very word mechanism, a suggestive and ambiguous expression, took on a host of different meanings. Emphasizing the important role of key ancient and early modern protagonists, from Galen to Robert Boyle, this book offers a historical investigation of the term mechanism from the late Renaissance to the end of the seventeenth century, at a time when it was used rather frequently in complex debates about the nature of the notion of the soul. In this rich and detailed study, Domenico Bertoloni Melifocuses on strategies for discussing the notion of mechanism in historically sensitive ways; the relation between mechanism, visual representation, and anatomy; the usage and meaning of the term in early modern times; and Marcello Malpighi and the problems of fecundation and generation, among the most challenging topics to investigate from a mechanistic standpoint.
Book Synopsis A Mechanistic Study of 1,3 Eliminations in the Norbornyl System by : Nick Henry Werstiuk
Download or read book A Mechanistic Study of 1,3 Eliminations in the Norbornyl System written by Nick Henry Werstiuk and published by . This book was released on 1966 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Mechanistic Study of 3-methylene-1,4-cyclohexadiene (p̲-isotoluene),5-methylene-1,3-cyclohexadiene (o̲-isotoluene), 1-methylene-1,4-dihydronaphthalene (benzo-p̲-dimethylbicyclo[4.1.1]octa-2,4-d̲i̲e̲n̲e̲, and Tetramethyl-1,3-benzoquinodimethane (tetramethyl-1,3-xylylene) by : Andrea M. Gortva
Download or read book A Mechanistic Study of 3-methylene-1,4-cyclohexadiene (p̲-isotoluene),5-methylene-1,3-cyclohexadiene (o̲-isotoluene), 1-methylene-1,4-dihydronaphthalene (benzo-p̲-dimethylbicyclo[4.1.1]octa-2,4-d̲i̲e̲n̲e̲, and Tetramethyl-1,3-benzoquinodimethane (tetramethyl-1,3-xylylene) written by Andrea M. Gortva and published by . This book was released on 1986 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download A Mechanistic Study of 3-methylene-1,4-cyclohexadiene (p̲-isotoluene),5-methylene-1,3-cyclohexadiene (o̲-isotoluene), 1-methylene-1,4-dihydronaphthalene (benzo-p̲-dimethylbicyclo[4.1.1]octa-2,4-d̲i̲e̲n̲e̲, and Tetramethyl-1,3-benzoquinodimethane (tetramethyl-1,3-xylylene) PDF Online Free](https://books.google.com/books/content/images/frontcover/X0UeAQAAMAAJ?fife=w200-h370)
