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A Landmark Repurposed
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Book Synopsis A Landmark Repurposed by : Christine Kreyling
Download or read book A Landmark Repurposed written by Christine Kreyling and published by . This book was released on 2021 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book was originally published in conjunction with the exhibition "From Post Office to Art Center: A Nashville Landmark in Transition", April 8, 2001-February 24, 2002. Published to mark the occasion of our twentieth anniversary, this newly revised edition includes a preface from William R. Frist, current chair and president of the Frist Art Museum's board of trustees, and an epilogue from Susan H. Edwards, executive director and CEO"--
Book Synopsis Drug Repurposing by : Farid A. Badria
Download or read book Drug Repurposing written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2020-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.
Book Synopsis Old Buildings, New Forms by : Francoise Bollack
Download or read book Old Buildings, New Forms written by Francoise Bollack and published by The Monacelli Press, LLC. This book was released on 2013-11-12 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is clear that working with historic structures is both more environmentally sustainable and cost effective than new architecture and construction—and many believe that the best design occurs at the intersection of old and new. Françoise Astorg Bollack presents 28 examples gathered in the United States and throughout Europe and the Middle East. Some are well known—Mass MOCA, Market Santa Caterina in Barcelona, Neues Museum in Berlin—and others are almost anonymous. But all demonstrate a unique and appropriate solution to the problem of adapting historic structures to contemporary uses. This survey of contemporary additions to older buildings is an essential addition to the architectural literature. “I have always loved old buildings. An old building is not an obstacle but instead a foundation for continued action. Designing with them is an exhilarating enterprise; adding to them, grafting, inserting, knitting new pieces into the existing built fabric is endlessly stimulating.” —Françoise Astorg Bollack
Book Synopsis Drug Repurposing and Computational Drug Discovery by : Mithun Rudrapal
Download or read book Drug Repurposing and Computational Drug Discovery written by Mithun Rudrapal and published by CRC Press. This book was released on 2023-10-27 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing is defined as identifying new pharmacological indications from old, existing, failed, investigational, already marketed, or FDA-approved drugs and prodrugs, and applying these new uses in the treatment of diseases other than the drug’s original intended therapeutic use. The application of computational techniques in discovery research not only helps in the development of drugs from leads or existing drug molecules but can also be useful for the repurposing of existing drug candidates. This new volume presents exciting recent advances in drug repurposing and computational approaches for the discovery and development of drugs against certain difficult-to-treat and life-threatening diseases. With contributions from a global team of experts (academicians, scientists, and researchers), it explores the sophisticated tools and techniques of drug repurposing and computational drug discovery. It delivers valuable information on computational techniques, tools, and databases being utilized for drug repurposing and for identifying the uses of existing drug candidates on different emerging or deadly diseases. Drug repurposing and computational approaches addressed in the book target the discovery and development of drugs for microbial infections (bacterial, fungal, viral, COVID-19), parasitic diseases and neglected tropical diseases (NTDs), malignant diseases (cancer), inflammatory diseases, cardiovascular disorders, diabetes, and aging and neurological (CNS) disorders. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions.
Book Synopsis 1950s American Style: A Reference Guide (soft cover) by : Daniel Niemeyer
Download or read book 1950s American Style: A Reference Guide (soft cover) written by Daniel Niemeyer and published by Lulu.com. This book was released on 2013 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Facets of the Fifties. A reference guide to an iconic Decade of Movie Palaces, Television, Classic Cars, Sports, Department Stores, Trains, Music, Food, Fashion and more
Download or read book Making Bourbon written by Karl Raitz and published by University Press of Kentucky. This book was released on 2020-03-17 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: While other industries chase after the new and improved, bourbon makers celebrate traditions that hearken back to an authentic frontier craft. Distillers enshrine local history in their branding and time-tested recipes, and rightfully so. Kentucky's unique geography shaped the whiskeys its settlers produced, and for more than two centuries, distilling bourbon fundamentally altered every aspect of Kentucky's landscape and culture. Making Bourbon: A Geographical History of Distilling in Nineteenth-Century Kentucky illuminates how the specific geography, culture, and ecology of the Bluegrass converged and gave birth to Kentucky's favorite barrel-aged whiskey. Expanding on his fall 2019 release Bourbon's Backroads, Karl Raitz delivers a more nuanced discussion of bourbon's evolution by contrasting the fates of two distilleries in Scott and Nelson Counties. In the nineteenth century, distilling changed from an artisanal craft practiced by farmers and millers to a large-scale mechanized industry. The resulting infrastructure—farms, mills, turnpikes, railroads, steamboats, lumberyards, and cooperage shops—left its permanent mark on the land and traditions of the commonwealth. Today, multinational brands emphasize and even construct this local heritage. This unique interdisciplinary study uncovers the complex history poured into every glass of bourbon.
Author :Kathleen de la Pena McCook Publisher :American Library Association ISBN 13 :083891506X Total Pages :432 pages Book Rating :4.8/5 (389 download)
Book Synopsis Introduction to Public Librarianship, Third Edition by : Kathleen de la Pena McCook
Download or read book Introduction to Public Librarianship, Third Edition written by Kathleen de la Pena McCook and published by American Library Association. This book was released on 2018-12-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Put simply, there is no text about public librarianship more rigorous or comprehensive than McCook's survey. Now, the REFORMA Lifetime Achievement Award-winning author has teamed up with noted public library scholar and advocate Bossaller to update and expand her work to incorporate the field's renewed emphasis on outcomes and transformation. This "essential tool" (Library Journal) remains the definitive handbook on this branch of the profession. It covers every aspect of the public library, from its earliest history through its current incarnation on the cutting edge of the information environment, including statistics, standards, planning, evaluations, and results;legal issues, funding, and politics;organization, administration, and staffing;all aspects of library technology, from structure and infrastructure to websites and makerspaces;adult services, youth services, and children's services;associations, state library agencies, and other professional organizations;global perspectives on public libraries; andadvocacy, outreach, and human rights. Exhaustively researched and expansive in its scope, this benchmark text continues to serve both LIS students and working professionals.
Download or read book Bee Time written by Mark L. Winston and published by Harvard University Press. This book was released on 2014-10-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Being among bees is a full-body experience, Mark Winston writes—from the low hum of tens of thousands of insects and the pungent smell of honey and beeswax, to the sight of workers flying back and forth between flowers and the hive. The experience of an apiary slows our sense of time, heightens our awareness, and inspires awe. Bee Time presents Winston’s reflections on three decades spent studying these creatures, and on the lessons they can teach about how humans might better interact with one another and the natural world. Like us, honeybees represent a pinnacle of animal sociality. How they submerge individual needs into the colony collective provides a lens through which to ponder human societies. Winston explains how bees process information, structure work, and communicate, and examines how corporate boardrooms are using bee societies as a model to improve collaboration. He investigates how bees have altered our understanding of agricultural ecosystems and how urban planners are looking to bees in designing more nature-friendly cities. The relationship between bees and people has not always been benign. Bee populations are diminishing due to human impact, and we cannot afford to ignore what the demise of bees tells us about our own tenuous affiliation with nature. Toxic interactions between pesticides and bee diseases have been particularly harmful, foreshadowing similar effects of pesticides on human health. There is much to learn from bees in how they respond to these challenges. In sustaining their societies, bees teach us ways to sustain our own.
Book Synopsis Drug Repurposing by : Ramarao Poduri
Download or read book Drug Repurposing written by Ramarao Poduri and published by Walter de Gruyter GmbH & Co KG. This book was released on 2023-10-02 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery. The book describes tools and techniques for identifying new therapeutic potentials for existing drugs and covers the repurposing of drugs from synthetic and natural origin. It compares the costs of drug repurposing with traditional drug discovery and discusses challenges and future perspectives of drug repurposing.
Book Synopsis Drug Repurposing in Cancer Therapy by : Kenneth K.W. To
Download or read book Drug Repurposing in Cancer Therapy written by Kenneth K.W. To and published by Academic Press. This book was released on 2020-07-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types
Book Synopsis Frontiers In Medicinal Chemistry: Volume 10 by : Ashok Kumar Jha
Download or read book Frontiers In Medicinal Chemistry: Volume 10 written by Ashok Kumar Jha and published by Bentham Science Publishers. This book was released on 2023-10-27 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Medicinal Chemistry is a book series devoted to reviews on research topics relevant to medicinal chemistry and allied disciplines. Frontiers in Medicinal Chemistry covers developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships. This book series is essential for any medicinal chemist who wishes to be updated on the latest and the most important advances in the field.This is the tenth volume of the series. The extensive volume brings 11 reviews on a variety of topics including anti-cancer drug therapeutics, food chemistry, toxicology and drug development strategies. The list of topics in this volume includes:Isoxazole derivatives as potential pharmacophore for new drug developmentContemporary trends in drug repurposing: identifying new targets for existing drugsPharmaceutical potential of pyrimidines as antiviral agentsDrugs and phytochemicals targeting cancerHarnessing the neurological properties of indian brain health booster brahmiCarcinogenicity of hexavalent chromium and its effectsMedicinal plants: a future of modern medical systemShikonin, a naphthaquinone of commercial importance: its biosynthesis and prospect for use as drugsFast foods: chemical composition and implications for healthImplications of DNA-acting agents as anticarcinogenic potential in breast cancer therapeuticsAloe vera - a medicinal plant as potential therapeutic agents for liver cancer
Book Synopsis Last Orders! Middlesbrough's Lost & Historic Pubs by : Tosh Warwick
Download or read book Last Orders! Middlesbrough's Lost & Historic Pubs written by Tosh Warwick and published by Heritage Unlocked. This book was released on 2023-12-10 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring over 150 photos of pubs from across the decades, Last Orders! Middlesbrough’s Lost and Historic Pubs is inspired by the Les Bulman Collection at Teesside Archives. The book features previously unseen photographs and incredible accounts and memories of life in Middlesbrough’s famous pubs, bars and clubs including the Captain Cook, The Masham, The Shakespeare, Acklam Hotel, The Zetland, Billy Paul’s, The Madison and Club Bongo International.
Book Synopsis Jerusalem and Other Holy Places as Foci of Multireligious and Ideological Confrontation by :
Download or read book Jerusalem and Other Holy Places as Foci of Multireligious and Ideological Confrontation written by and published by BRILL. This book was released on 2020-12-07 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jerusalem and Other Holy Places as Foci of Multireligious and Ideological Confrontation demonstrates the variety in the study of holy places, as well as the flexibility of geographic and historical aspects of holiness.
Book Synopsis Vanished Denver Landmarks by : Mark A. Barnhouse
Download or read book Vanished Denver Landmarks written by Mark A. Barnhouse and published by Arcadia Publishing. This book was released on 2021-10-11 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: From its 1858 birth, the Mile High City has undergone continuous change, with each successive generation putting its stamp on Denver's architectural character. Along the way, landmarks initially considered first class were later deemed disposable by those who had different visions of what Denver should be. Beloved buildings like the Tabor Grand Opera House, the Windsor Hotel and the Republic Building vanished. Historian Mark A. Barnhouse revisits these lost treasures along with the lesser known and rarely explored, including an apartment building dubbed "Denver's Bohemia," the humble abode of one of the early twentieth century's most successful novelists and the opulent mansion of a man who gave Denver three consecutive baseball championships.
Book Synopsis Denver Landmarks and Historic Districts by : Thomas J. Noel
Download or read book Denver Landmarks and Historic Districts written by Thomas J. Noel and published by University Press of Colorado. This book was released on 2016-05-01 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Timberline Book Denver Landmarks and Historic Districts, Second Edition is the newest, most thorough guide to Denver’s 51 historic districts and more than 331 individually landmarked properties. This lavishly illustrated volume celebrates Denver’s oldest banks, churches, clubs, hotels, libraries, schools, restaurants, mansions, and show homes. Denver is unusually fortunate to retain much of its significant architectural heritage. The Denver Landmark Preservation Commission (1967), Historic Denver, Inc. (1970), Colorado Preservation, Inc. (1984), and History Colorado (1879) have all worked to identify and preserve Denver buildings notable for architectural, geographical, or historical significance. Since the 1970s, Denver has designated more landmarks than any other US city of comparable size. Many of these landmarks, both well-known and obscure, are open to the public. These landmarks and districts have helped make Denver one of the healthiest and most attractive core cities in the United States, transforming what was once Skid Row into the Lower Downtown Historic District of million-dollar lofts and $7 craft beers. Entries include the Daniels & Fisher Tower, the Brown Palace Hotel, Red Rocks Outdoor Amphitheatre, Elitch Theatre, Fire Station No. 7, the Richthofen Castle, the Washington Park Boathouse and Pavilion, and the Capitol Hill, Five Points, and Highlands historic districts. Denver Landmarks and Historic Districts highlights the many officially designated buildings and neighborhoods of note. This crisply written guide serves as a great starting point for rubbernecking around Denver, whether by motor vehicle, by bicycle, or afoot.
Download or read book Citizen Jean written by Jean Godden and published by Washington State University Press. This book was released on 2021-06-18 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jean Godden lived in more than 100 cities and towns before she moved to Seattle. It was simply “the most spectacular place” she had ever seen. There, she married, finished her schooling, raised her children, and spent two decades as a reporter, editor, and columnist with the Seattle Post-Intelligencer and Seattle Times. It also was where she served as an activist and city councilmember, working toward reducing the country’s largest gender wage gap and championing paid parental leave. Godden witnessed historic events, watched Seattle evolve into a civic and national affairs leader, met city and state movers and shakers, and became a local celebrity herself. In Citizen Jean, the consummate observer recounts--as only she can--the World’s Fair that got Seattle noticed, the citizen-led battle against freeways, the fight to keep Pike Place Market away from New York investors, the World Trade Organization protests, and more. She shares personal insights, delivers an insider’s view of the city’s newspaper strikes and rivalry, and casts a revealing look at regional politicians. “For years, those of us who love our city have taken special pleasure that Jean was there with us, notebook in hand, pencil poised, madly scribbling what would become, in print, the most clever, insightful and profound reflections on the place we call home. From her first days as a reporter, to her days on the city council and beyond, Jean Godden and her ubiquitous notebook have been the essential guide to life in Seattle.”--from the Foreword by Leonard Garfield, Executive Director, Museum of History and Industry
Download or read book Interior Landmarks written by and published by The Monacelli Press, LLC. This book was released on 2015-09-29 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some are widely celebrated—Radio City Music Hall, the Great Hall of the Metropolitan Museum of Art, Grand Central Station—and others virtually unknown, all warrant preservation. This book is the first to present great landmarked interiors of New York in all their intricate detail, in a visual celebration of space that captures the rich heritage of the city. In the fifty years since it was established in 1965, the New York City Landmarks Law has preserved for generations to come a remarkable number of significant buildings that represent New York City’s cultural, social, economic, political, and architectural history. Not only do the exterior facades of these buildings fall within the law’s purview, but, since 1973, many of their stunning interiors as well. This book tells the colorful stories of 47 interior landmarks from the oldest to the youngest—from the grand Italianate and infamous Tweed Courthouse, the centerpiece of the largest corruption case in New York history, and the glamorous Art Deco Rainbow Room, constructed shortly after the repeal of the Prohibition—to the modernist 1967 Ford Foundation Building, whose garden-filled atrium exemplified sustainable design well before the concept became fashionable, and was hailed as “one of the most romantic environments ever devised by corporate man.” Located throughout the five boroughs, the interior landmarks include banks, theaters, office building lobbies, restaurants, libraries, and more—spaces in which New Yorkers have worked, learned, governed, been entertained, and interacted with their communities for decades. Readers will learn about their original construction and style, their exceptional design features, materials, and architectural details—then of the challenges to preserving them—whether they were unanimously accepted or hotly contested in legal battles—the restorations or re-imaginings that took place, and the preservationists, philanthropists, politicians, and designers who made it possible. Combining strong visuals and thorough research, this valuable reference work will fascinate all readers with an interest in the city’s history.
