A Guide To The Hplc Literature

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HPLC Methods for Clinical Pharmaceutical Analysis

Author : Hermann Mascher
Publisher : John Wiley & Sons
ISBN 13 : 3527331298
Total Pages : 0 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis HPLC Methods for Clinical Pharmaceutical Analysis by : Hermann Mascher

Download or read book HPLC Methods for Clinical Pharmaceutical Analysis written by Hermann Mascher and published by John Wiley & Sons. This book was released on 2012-02-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a gap in the literature for a hands-on guide focusing on everyday laboratory challenges, this English edition has been expanded and revised using the feedback received on the successful German precursor. Throughout the book, Professor Mascher draws on his 30 years of experience and provides abundant practical advice, troubleshooting and other hints highlighted in boxes, as well as a broad selection of walkthrough case studies. Based on a course taught by the author, the first part of the book intuitively explains all steps of routine bioanalysis and explains how to set up a robust, inexpensive and effi cient method for a given substance. In the second part he includes 20 worked example cases that highlight common challenges and how to overcome them. With its appendix containing tried-and-tested analytical methods for 100 clinically relevant substances from the author`s own laboratory, complete with spectral and MS data as well as literature references and basic pharmacokinetic information, this is a life-long companion for everyone working in clinical, pharmaceutical and biochemical analysis. Comments to the German book: "The book comes to life through its examples, showing not only what did work in the author's laboratory, but also what didn't." ChemieReport "Indispensable for novices, while even old hands will be able to expand their knowledge. A collection of analytical data for ca. 100 substances completes the book's offering, leaving almost nothing to be desired." pharmind

HPLC

Author : Toshihiko Hanai
Publisher : Royal Society of Chemistry
ISBN 13 : 9780854045150
Total Pages : 152 pages
Book Rating : 4.0/5 (451 download)

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Book Synopsis HPLC by : Toshihiko Hanai

Download or read book HPLC written by Toshihiko Hanai and published by Royal Society of Chemistry. This book was released on 1999 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can these compounds be separated? Why was that method used? These are the two basic questions often asked by students of chromatography. HPLC: A Practical Guide provides the answers, enabling the reader to grasp the concepts of the technique using simple, representative chromatograms. Divided into six chapters, this practical guide covers basic concepts of HPLC; instrumentation; stationary phase materials; eluents; column efficiency; and the influence of physical chemistry on separations. Focusing on the basic considerations such as selection of stationary phase and eluent, rather than specific applications, sections on troubleshooting are also included. Uniquely, the descriptions of chromatographic separations are based on solubility using molecular properties, and solubility parameters are used to analyse the selections of chromatographic mode and column. Presenting the chemistry of liquid chromatography for undergraduate students, this valuable practical guide will also be useful for laboratory staff in industry and academia.

Selection of the HPLC Method in Chemical Analysis

Author : Serban C. Moldoveanu
Publisher : Elsevier
ISBN 13 : 0128037113
Total Pages : 600 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Selection of the HPLC Method in Chemical Analysis by : Serban C. Moldoveanu

Download or read book Selection of the HPLC Method in Chemical Analysis written by Serban C. Moldoveanu and published by Elsevier. This book was released on 2016-11-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation. High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away from the critical aspects of HPLC method selection. For the first time, a systematic approach for sorting through the available information and reviewing critically the up-to-date progress in HPLC for selecting a specific analysis is available in a single book. Selection of the HPLC Method in Chemical Analysis is an inclusive go-to reference for HPLC method selection, development, and validation. - Addresses the various aspects of practice and instrumentation needed to obtain reliable HPLC analysis results - Leads researchers to the best choice of an HPLC method from the overabundance of information existent in the field - Provides criteria for HPLC method selection, development, and validation - Authored by world-renowned HPLC experts who have more than 60 years of combined experience in the field

A Guide to the HPLC Literature

Author : Henri Colin
Publisher :
ISBN 13 :
Total Pages : 598 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis A Guide to the HPLC Literature by : Henri Colin

Download or read book A Guide to the HPLC Literature written by Henri Colin and published by . This book was released on 1984 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Practical Handbook of Preparative HPLC

Author : Donald A Wellings
Publisher : Elsevier
ISBN 13 : 0080458858
Total Pages : 193 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis A Practical Handbook of Preparative HPLC by : Donald A Wellings

Download or read book A Practical Handbook of Preparative HPLC written by Donald A Wellings and published by Elsevier. This book was released on 2011-04-18 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries for the analysis and purification of drugs, small molecules, proteins and DNA.This book...•Provides practical, hands-on advice based on years of experience•Will help ensure optimal design, equipment and separation results for your particular task•Presents system layouts from laboratory to process scale•Will help you to devise or improve record-keeping and documentation systems·Provides practical, hands-on advice based on years of experience·Will help ensure optimal design, equipment and separation results for your particular task·Presents system layouts from laboratory to process scale·Will help you to devise or improve record-keeping and documentation systems

A Guide to the HPLC Literature: 1966-1979

Author : Henri Colin
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 968 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Guide to the HPLC Literature: 1966-1979 by : Henri Colin

Download or read book A Guide to the HPLC Literature: 1966-1979 written by Henri Colin and published by Wiley-Interscience. This book was released on 1984 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Modern Liquid Chromatography

Author : Lloyd R. Snyder
Publisher : John Wiley & Sons
ISBN 13 : 1118210395
Total Pages : 831 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Introduction to Modern Liquid Chromatography by : Lloyd R. Snyder

Download or read book Introduction to Modern Liquid Chromatography written by Lloyd R. Snyder and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

A Guide to the HPLC Literature: 1980-1981

Author : Henri Colin
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 984 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis A Guide to the HPLC Literature: 1980-1981 by : Henri Colin

Download or read book A Guide to the HPLC Literature: 1980-1981 written by Henri Colin and published by Wiley-Interscience. This book was released on 1984 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: HPLC has largely contributed to the development of pharmacology, biology, food research and the biomedical sciences, as demonstrated by the growing number of meetings dedicated to this topic and by the proliferation of companies offering equipment, products or services for HPLC users. It is becoming highly difficult to follow the current literature, particularly in the area of applications.

Handbook of Pharmaceutical Analysis by HPLC

Author : Satinder Ahuja
Publisher : Elsevier
ISBN 13 : 0080455182
Total Pages : 679 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Pharmaceutical Analysis by HPLC by : Satinder Ahuja

Download or read book Handbook of Pharmaceutical Analysis by HPLC written by Satinder Ahuja and published by Elsevier. This book was released on 2005-02-09 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

HPLC

Author : Marvin C. McMaster
Publisher : John Wiley & Sons
ISBN 13 : 0471754013
Total Pages : 252 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis HPLC by : Marvin C. McMaster

Download or read book HPLC written by Marvin C. McMaster and published by John Wiley & Sons. This book was released on 2006-12-18 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Second Edition of the classic handbook details how to set up an HPLC system that capitalizes on the latest innovations. It covers new techniques in high-temperature, micro-flow, and ultra-fast chromatography, the linking of an HPLC to a mass spectrometer, and more. Complete appendices and supplementary material online, this guide has everything chromatographers need to know to confidently separate, identify, purify, and quantify compounds.

Troubleshooting HPLC Systems

Author : Paul C. Sadek
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Troubleshooting HPLC Systems by : Paul C. Sadek

Download or read book Troubleshooting HPLC Systems written by Paul C. Sadek and published by Wiley-Interscience. This book was released on 2000 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete, up-to-date guide to the use, maintenance, and troubleshooting of HPLC systems The last twenty-five years have seen a dramatic rise in the use of High Performance Liquid Chromatography (HPLC) in laboratories worldwide. Troubleshooting HPLC Systems provides analysts as well as laboratory technicians and managers with a readily accessible and immensely useful guide to the new generation of HPLC equipment and techniques. With an emphasis on effective troubleshooting of HPLC systems, this lab companion covers system configuration and functions, problem-solving procedures, maintenance, and HPLC basics. It then walks chromatographers investigating the source of a malfunction through each system component-from solvents and reservoirs to sample preparation to columns and detectors. Special features of Troubleshooting HPLC Systems include: * A detailed review of HPLC instrumentation and accessories * The role of operating parameters as indicators of system performance * Step-by-step troubleshooting protocols for each system component * How to set up a preventive maintenance program for HPLC systems * An overview of the categories of HPLC separations * A compilation of HPLC terms and definitions * Tables and charts detailing solvents' properties

HPLC and UHPLC for Practicing Scientists

Author : Michael W. Dong
Publisher : John Wiley & Sons
ISBN 13 : 1119313767
Total Pages : 410 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis HPLC and UHPLC for Practicing Scientists by : Michael W. Dong

Download or read book HPLC and UHPLC for Practicing Scientists written by Michael W. Dong and published by John Wiley & Sons. This book was released on 2019-07-23 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise yet comprehensive reference guide on HPLC/UHPLC that focuses on its fundamentals, latest developments, and best practices in the pharmaceutical and biotechnology industries Written for practitioners by an expert practitioner, this new edition of HPLC and UHPLC for Practicing Scientists adds numerous updates to its coverage of high-performance liquid chromatography, including comprehensive information on UHPLC (ultra-high-pressure liquid chromatography) and the continuing migration of HPLC to UHPLC, the modern standard platform. In addition to introducing readers to HPLC’s fundamentals, applications, and developments, the book describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. HPLC and UHPLC for Practicing Scientists, Second Edition offers three new chapters. One is a standalone chapter on UHPLC, covering concepts, benefits, practices, and potential issues. Another examines liquid chromatography/mass spectrometry (LC/MS). The third reviews at the analysis of recombinant biologics, particularly monoclonal antibodies (mAbs), used as therapeutics. While all chapters are revised in the new edition, five chapters are essentially rewritten (HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects). The book also includes problem and answer sections at the end of each chapter. Overviews fundamentals of HPLC to UHPLC, including theories, columns, and instruments with an abundance of tables, figures, and key references Features brand new chapters on UHPLC, LC/MS, and analysis of recombinant biologics Presents updated information on the best practices in method development, validation, operation, troubleshooting, and maintaining regulatory compliance for both HPLC and UHPLC Contains major revisions to all chapters of the first edition and substantial rewrites of chapters on HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects Includes end-of-chapter quizzes as assessment and learning aids Offers a reference guide to graduate students and practicing scientists in pharmaceutical, biotechnology, and other industries Filled with intuitive explanations, case studies, and clear figures, HPLC and UHPLC for Practicing Scientists, Second Edition is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology. It will be a great benefit to every busy laboratory analyst and researcher.

HPLC for Pharmaceutical Scientists

Author : Yuri V. Kazakevich
Publisher : John Wiley & Sons
ISBN 13 : 0470087943
Total Pages : 1136 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis HPLC for Pharmaceutical Scientists by : Yuri V. Kazakevich

Download or read book HPLC for Pharmaceutical Scientists written by Yuri V. Kazakevich and published by John Wiley & Sons. This book was released on 2007-02-16 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

Basic HPLC and CE of Biomolecules

Author : Robert L. Cunico
Publisher : Bay Bioanalytical Laboratory, Incorporated
ISBN 13 : 9780966322903
Total Pages : 0 pages
Book Rating : 4.3/5 (229 download)

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Book Synopsis Basic HPLC and CE of Biomolecules by : Robert L. Cunico

Download or read book Basic HPLC and CE of Biomolecules written by Robert L. Cunico and published by Bay Bioanalytical Laboratory, Incorporated. This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Practical HPLC Method Development

Author : Lloyd R. Snyder
Publisher : John Wiley & Sons
ISBN 13 : 1118591518
Total Pages : 665 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Practical HPLC Method Development by : Lloyd R. Snyder

Download or read book Practical HPLC Method Development written by Lloyd R. Snyder and published by John Wiley & Sons. This book was released on 2012-12-03 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revision brings the reader completely up to date on the evolving methods associated with increasingly more complex sample types analyzed using high-performance liquid chromatography, or HPLC. The book also incorporates updated discussions of many of the fundamental components of HPLC systems and practical issues associated with the use of this analytical method. This edition includes new or expanded treatments of sample preparation, computer assisted method development, as well as biochemical samples, and chiral separations.

Hydrophilic Interaction Chromatography

Author : Bernard A. Olsen
Publisher : John Wiley & Sons
ISBN 13 : 1118054172
Total Pages : 336 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Hydrophilic Interaction Chromatography by : Bernard A. Olsen

Download or read book Hydrophilic Interaction Chromatography written by Bernard A. Olsen and published by John Wiley & Sons. This book was released on 2013-01-22 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how to use HILIC to analyze and better understand polar compounds An increasingly popular analytical method, hydrophilic interaction chromatography (HILIC) has the ability to retain and separate polar compounds that are often difficult to analyze by reversed-phase high-performance liquid chromatography (HPLC) or other analytical methods. Offering a comprehensive review, this book enables readers to develop a fundamental understanding of how HILIC works and then apply that knowledge to develop and implement a variety of practical applications. Hydrophilic Interaction Chromatography begins with discussions of HILIC retention mechanisms, stationary phases, and general method development. This sets the foundation for the book's extensive coverage of applications. The authors address unique separation challenges for bioanalytical, environmental, pharmaceutical, and biochemical applications. Moreover, there is a thorough discussion of HILIC in two-dimensional chromatography. With contributions from leading analytical scientists who have extensive experience in HILIC as well as HPLC, Hydrophilic Interaction Chromatography serves as a practical guide for researchers, featuring: Detailed examples of HILIC methods and development approaches Thorough explanations of retention mechanisms and the impact of stationary phase and mobile phase properties on separations Step-by-step guidance for developing efficient, sensitive, and robust HILIC methods References to the primary literature at the end of each chapter Hydrophilic Interaction Chromatography is written for scientists who use or develop analytical methods for the separation of polar compounds. In particular, these researchers will discover how HILIC can be used to analyze and better understand the composition of pharmaceutical, bioanalytical, biochemical, chemical, food, and environmental samples.

High Performance Liquid Chromatography

Author : Sandie Lindsay
Publisher : John Wiley & Sons
ISBN 13 : 0471931152
Total Pages : 370 pages
Book Rating : 4.4/5 (719 download)

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Book Synopsis High Performance Liquid Chromatography by : Sandie Lindsay

Download or read book High Performance Liquid Chromatography written by Sandie Lindsay and published by John Wiley & Sons. This book was released on 1992-07-27 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: High performance liquid chromatography is the most powerful of all the chromatographic techniques, often achieving separations and analyses that would be difficult or impossible with other forms of chromatography. This study and training text examines the concepts and techniques used in this field. A selection of literature available from equipment manufacturers is included along with a brief review of some more specialized topics.