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Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 882 pages
Book Rating : 4.3/5 (91 download)
Download or read book Journal written by National Cancer Institute (U.S.) and published by . This book was released on 1968 with total page 882 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michel Lebel
Publisher : Springer Science & Business Media
ISBN 13 : 9780306482335
Total Pages : 172 pages
Book Rating : 4.4/5 (823 download)
Download or read book Molecular Mechanisms of Werner’s Syndrome written by Michel Lebel and published by Springer Science & Business Media. This book was released on 2004-09-14 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: During our short time on earth, we all undergo the highly complex process of aging, and with it, we experience the many physiological symptoms. Studies of premature aging have produced a great deal of information that gives some aspects of aging a better understanding. This book explores Werner's syndrome. To some, Werner's syndrome is considered a caricature of aging, but others will find it fascinating that only one mutated human gene (WRN) can bring about a multitude of complicated phenotypes that are usually associated with aging.
Author :
Publisher : Academic Press
ISBN 13 : 0128225351
Total Pages : 258 pages
Book Rating : 4.1/5 (282 download)
Download or read book Carcinogen-Driven Mouse Models of Oncogenesis written by and published by Academic Press. This book was released on 2021-03-28 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more. Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more. Provides protocols provided by renowned experts in the field Presents detailed descriptions of protocols, hence allowing appropriate reproduction of the models Includes author notes for each protocol, covering useful tips and troubleshooting
Author :
Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.E/5 ( download)
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1981 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0080562051
Total Pages : 321 pages
Book Rating : 4.0/5 (85 download)
Download or read book Advances in Cancer Research written by and published by Academic Press. This book was released on 1976-05-24 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research
Author :
Publisher :
ISBN 13 :
Total Pages : 926 pages
Book Rating : 4.E/5 ( download)
Download or read book Carcinogenesis Abstracts written by and published by . This book was released on 1978 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kumar, Sumit
Publisher : IGI Global
ISBN 13 : 1799865312
Total Pages : 913 pages
Book Rating : 4.7/5 (998 download)
Download or read book Handbook of Research on Advancements in Cancer Therapeutics written by Kumar, Sumit and published by IGI Global. This book was released on 2020-11-27 with total page 913 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complexity of cancer demands an integrated approach from both a cancer biology standpoint and a pharmaceutical basis to understand the different anticancer modalities. Current research has been focused on conventional and newer anticancer modalities, recent discoveries in cancer research, and also the advancements in cancer treatment. There is a current need for more research on the advances in cancer therapeutics that bridge the gap between basic research (pharmaceutical drug development processes, regulatory issues, and translational experimentation) and clinical application. Recent promising discoveries such as immunotherapies, promising therapies undergoing clinical trials, synthetic lethality, carbon beam radiation, and other exciting targeted therapies are being studied to improve and advance the studies of modern cancer treatment. The Handbook of Research on Advancements in Cancer Therapeutics serves as a comprehensive guide in modern cancer treatment by combining and merging the knowledge from both cancer biology and the pharmacology of anticancer modalities. The chapters come from multi-disciplinary backgrounds, including scientists and clinicians from both academia and various industries, to discuss nascent personalized therapies and big data-driven cancer treatment. While highlighting topic areas that include cancer prevention, cancer therapeutics, and cancer treatments through the lenses of technology, medicine/drugs, and alternate therapies, this book is ideally intended for oncologists, radiation oncologists, surgical oncologists, and cancer biologists, along with practitioners, stakeholders, researchers, academicians, and students who are interested in understanding the most fundamental aspects of cancer and the available therapeutic opportunities.
Author : A. Pullman
Publisher : Springer Science & Business Media
ISBN 13 : 9400991045
Total Pages : 581 pages
Book Rating : 4.4/5 (9 download)
Download or read book Carcinogenesis: Fundamental Mechanisms and Environmental Effects written by A. Pullman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 13th Jerusalem Symposium on Quantum Chemistry and Biochemistry held in Jerusalem, Israel, April 28-May 2, 1980
Author : A. Kappas
Publisher : Springer Science & Business Media
ISBN 13 : 1461538084
Total Pages : 276 pages
Book Rating : 4.4/5 (615 download)
Download or read book Mechanisms of Environmental Mutagenesis-Carcinogenesis written by A. Kappas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.
Author : H.F. Stich
Publisher : Springer Science & Business Media
ISBN 13 : 1461258472
Total Pages : 535 pages
Book Rating : 4.4/5 (612 download)
Download or read book Short-Term Tests for Chemical Carcinogens written by H.F. Stich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent surge of interest in designing, validating, and implementing short-term tests for carcinogens has been spurred by the fairly convincing correlation be tween the carcinogenicity and mutagenicity of chemicals and physical agents and by the assumption that DNA alteration, mutations, and chromosome aberrations are somehow involved in neoplastic transformation. Moreover, it has been tacitly assumed that the mutagenic capacity alone of compounds would induce regulatory agencies to pass rules for their removal from the environment and would lead the public to avoid them. The actual response, however, is quite different. Governmental departments shy away from making any decisions on the basis of in vitro test systems. The public at large is becoming irritated by daily an nouncements that many of their cherished habits could adversely affect their health. Industry appears to feel threatened and may reduce its search for new beneficial chemicals. The reluctance to accept wholeheartedly the mutagenicity tests for the detection of carcinogens is partly due to uncertainty about the in volvement of mutations in neoplastic transformation, partly due to the present difficulty of extrapolating results from various endpoints obtained on numerous organisms to man, and partly due to a multitude of complex events that lead in vivo to the evolvement of benign or malignant tumors.
Author : S. Garattini
Publisher : Springer Science & Business Media
ISBN 13 : 9400919042
Total Pages : 237 pages
Book Rating : 4.4/5 (9 download)
Download or read book The Importance of Animal Experimentation for Safety and Biomedical Research written by S. Garattini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists are coming under increasing pressure from activist groups to stop animal experimentation, branded as cruel and unnecessary for improving human health. This attitude, however, stems from an unrealistic evaluation of the situation and distorted information about present scientific knowledge. There is no question that most medical progress - perhaps all, in fac- has been attained through knowledge derived initially from experiments in various animal species. There is practically no way of replacing animals in these investigations and so-called 'alternative methods' are in reality merely complementary. Tissue cultures, cell, microorganisms, enzymes, membranes, mathematical models - all are useful for preliminary screening tests and for testing hypotheses, but the complexity of a living organism is such that in vivo studies are essential before any test can responsibly be made in man. This book presents the proceedings of an international symposium organized in Strasbourg (October 24-25, 1988), with the aim of assessing present-day requirements as regards animal experimentation in research related to major medical and toxicological problems still awaiting solutions.
Author : Surajit Pathak
Publisher : Springer Nature
ISBN 13 : 9811938245
Total Pages : 1158 pages
Book Rating : 4.8/5 (119 download)
Download or read book Handbook of Animal Models and its Uses in Cancer Research written by Surajit Pathak and published by Springer Nature. This book was released on 2023-01-31 with total page 1158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression, formation, and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering, including CRISP/Cas9, in designing and developing animal models for cancer research. Further, it discusses strategies for modeling animals for investigating growth, metastasis, tumor-associated inflammation and microenvironment, cancer stem cells, tumor heterogeneity, and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers, clinicians, and health care.
Author : Albert P. Li
Publisher : CRC Press
ISBN 13 : 9780849388156
Total Pages : 508 pages
Book Rating : 4.3/5 (881 download)
Download or read book Genetic Toxicology written by Albert P. Li and published by CRC Press. This book was released on 1991-03-27 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Toxicology is a comprehensive book covering the historical perspective of genetic toxicology; basic mechanisms of mutations and chromosomal effects; health consequences of genetic damage, including cancer and inheritable mutations; properties of physical, chemical, and biological mutagens; risk assessment of human exposure to genotoxicants; and the current position of some government regulatory agencies in the United States on the issues of genetic toxicology. The book will be a useful reference for students and researchers in toxicology, genetics, cancer biology, and medicine who are interested in the basic and applied principles of genetic toxicology. It will also benefit industrial toxicologists, products registration specialists, and government regulatory specialists with responsibility for the safety evaluation of industrial and environmental agents.
Author :
Publisher :
ISBN 13 :
Total Pages : 990 pages
Book Rating : 4.:/5 (35 download)
Download or read book The British Journal of Cancer written by and published by . This book was released on 1977 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Cancer Institute (U.S.). Division of Cancer Cause and Prevention
Publisher :
ISBN 13 :
Total Pages : 1252 pages
Book Rating : 4.:/5 (48 download)
Download or read book Annual Report written by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention and published by . This book was released on 1976 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Raymond R. Tice
Publisher : Springer Science & Business Media
ISBN 13 : 1461334551
Total Pages : 648 pages
Book Rating : 4.4/5 (613 download)
Download or read book Genotoxic Effects of Airborne Agents written by Raymond R. Tice and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: For at least 40 years there has been a great interest in the problems created by infectious airborne agents and other toxic sub stances transported through the air. During the Second World War, this problem grew out of the very high incidence of upper respira tory infections appearing in new military recruits who were brought together in very large, open quarters. As a result, very interest ing methods were developed to measure these airborne agents, espe cially bacteria, and some important methods were refined for their control. These methods primarily concentrated on ultraviolet radia tion, propylene glycol and other means to reduce the dust in an en vironment. Because of the specialized circumstances at that time the whole consideration of airborne particles became prominent. Now, with the new strides in the recognition of mutagenic and carcinogenic effects attributed to exposure to airborne chemicals from today's technology, the problem has again become quite promi nent. The development of experimental chambers has made it possible to conduct studies under carefully controlled conditions.
Author : Hajime Ohigashi
Publisher : Springer Science & Business Media
ISBN 13 : 4431670173
Total Pages : 661 pages
Book Rating : 4.4/5 (316 download)
Download or read book Food Factors for Cancer Prevention written by Hajime Ohigashi and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemoprevention is currently regarded as one of the most promising avenues for the control of cancer, with human epidemiological and animal studies indicating that the risk of cancer may be modified by changes in diet. Over 100 papers are collected in this volume, the proceedings of the International Conference on Food Factors: Chemistry and Cancer Prevention, held in Hamamatsu, Japan, in December 1995. Special emphasis is placed on chemical, biological, and molecular properties of phytochemicals in teas, fruit, vegetables, herbs, and spices, and on their potential for cancer prevention. Also discussed are the cancer-preventive effects of vitamins, lipids, carotenoids, flavonoids, and other components of diet. The findings presented here will be invaluable to all who are interested in diet and cancer prevention, and especially to biochemists, pharmacologists, food scientists, and nutritionists.
